2WVR

Human Cdt1:Geminin complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003682	molecular_function	chromatin binding
A	0003712	molecular_function	transcription coregulator activity
A	0003714	molecular_function	transcription corepressor activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0006275	biological_process	regulation of DNA replication
A	0007346	biological_process	regulation of mitotic cell cycle
A	0008156	biological_process	negative regulation of DNA replication
A	0017053	cellular_component	transcription repressor complex
A	0030174	biological_process	regulation of DNA-templated DNA replication initiation
A	0042826	molecular_function	histone deacetylase binding
A	0045786	biological_process	negative regulation of cell cycle
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0065003	biological_process	protein-containing complex assembly
A	0140297	molecular_function	DNA-binding transcription factor binding
A	1903467	biological_process	negative regulation of mitotic DNA replication initiation
A	2000104	biological_process	negative regulation of DNA-templated DNA replication
B	0003682	molecular_function	chromatin binding
B	0003712	molecular_function	transcription coregulator activity
B	0003714	molecular_function	transcription corepressor activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0006275	biological_process	regulation of DNA replication
B	0007346	biological_process	regulation of mitotic cell cycle
B	0008156	biological_process	negative regulation of DNA replication
B	0017053	cellular_component	transcription repressor complex
B	0030174	biological_process	regulation of DNA-templated DNA replication initiation
B	0042826	molecular_function	histone deacetylase binding
B	0045786	biological_process	negative regulation of cell cycle
B	0045892	biological_process	negative regulation of DNA-templated transcription
B	0065003	biological_process	protein-containing complex assembly
B	0140297	molecular_function	DNA-binding transcription factor binding
B	1903467	biological_process	negative regulation of mitotic DNA replication initiation
B	2000104	biological_process	negative regulation of DNA-templated DNA replication
C	0000076	biological_process	DNA replication checkpoint signaling
C	0000278	biological_process	mitotic cell cycle
C	0000776	cellular_component	kinetochore
C	0003677	molecular_function	DNA binding
C	0003682	molecular_function	chromatin binding
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0006260	biological_process	DNA replication
C	0016604	cellular_component	nuclear body
C	0030174	biological_process	regulation of DNA-templated DNA replication initiation
C	0045740	biological_process	positive regulation of DNA replication
C	0045786	biological_process	negative regulation of cell cycle
C	0051301	biological_process	cell division
C	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
C	0070182	molecular_function	DNA polymerase binding
C	0071163	biological_process	DNA replication preinitiation complex assembly
C	0072708	biological_process	response to sorbitol
C	1902975	biological_process	mitotic DNA replication initiation
C	1902985	biological_process	mitotic pre-replicative complex assembly
C	2000104	biological_process	negative regulation of DNA-templated DNA replication

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	100
Details	Coiled coil: {"evidences":[{"source":"PubMed","id":"15260975","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15313623","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15378034","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24064211","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by MAPK8","evidences":[{"source":"PubMed","id":"21856198","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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