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2WVR

Human Cdt1:Geminin complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0003682molecular_functionchromatin binding
A0003714molecular_functiontranscription corepressor activity
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006275biological_processregulation of DNA replication
A0007346biological_processregulation of mitotic cell cycle
A0008156biological_processnegative regulation of DNA replication
A0009887biological_processanimal organ morphogenesis
A0017053cellular_componenttranscription repressor complex
A0030174biological_processregulation of DNA-templated DNA replication initiation
A0035563biological_processpositive regulation of chromatin binding
A0042826molecular_functionhistone deacetylase binding
A0045786biological_processnegative regulation of cell cycle
A0045892biological_processnegative regulation of DNA-templated transcription
A0065003biological_processprotein-containing complex assembly
A0071163biological_processDNA replication preinitiation complex assembly
A0140297molecular_functionDNA-binding transcription factor binding
A2000104biological_processnegative regulation of DNA-templated DNA replication
B0003682molecular_functionchromatin binding
B0003714molecular_functiontranscription corepressor activity
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006275biological_processregulation of DNA replication
B0007346biological_processregulation of mitotic cell cycle
B0008156biological_processnegative regulation of DNA replication
B0009887biological_processanimal organ morphogenesis
B0017053cellular_componenttranscription repressor complex
B0030174biological_processregulation of DNA-templated DNA replication initiation
B0035563biological_processpositive regulation of chromatin binding
B0042826molecular_functionhistone deacetylase binding
B0045786biological_processnegative regulation of cell cycle
B0045892biological_processnegative regulation of DNA-templated transcription
B0065003biological_processprotein-containing complex assembly
B0071163biological_processDNA replication preinitiation complex assembly
B0140297molecular_functionDNA-binding transcription factor binding
B2000104biological_processnegative regulation of DNA-templated DNA replication
C0000076biological_processDNA replication checkpoint signaling
C0000278biological_processmitotic cell cycle
C0000775cellular_componentchromosome, centromeric region
C0000776cellular_componentkinetochore
C0003677molecular_functionDNA binding
C0003682molecular_functionchromatin binding
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005654cellular_componentnucleoplasm
C0005694cellular_componentchromosome
C0006260biological_processDNA replication
C0016604cellular_componentnuclear body
C0030174biological_processregulation of DNA-templated DNA replication initiation
C0033262biological_processregulation of nuclear cell cycle DNA replication
C0035563biological_processpositive regulation of chromatin binding
C0045740biological_processpositive regulation of DNA replication
C0045786biological_processnegative regulation of cell cycle
C0051301biological_processcell division
C0051315biological_processattachment of mitotic spindle microtubules to kinetochore
C0070182molecular_functionDNA polymerase binding
C0071163biological_processDNA replication preinitiation complex assembly
C0072708biological_processresponse to sorbitol
C2000104biological_processnegative regulation of DNA-templated DNA replication
C2000105biological_processpositive regulation of DNA-templated DNA replication
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphothreonine; by MAPK8 => ECO:0000269|PubMed:21856198
ChainResidueDetails
CTHR29
BLYS27

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
CSER31
CSER380
ASER49
BSER34
BSER36
BSER49

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Phosphoserine; by MAPK8 => ECO:0000269|PubMed:21856198
ChainResidueDetails
CSER93
BSER63

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphoserine; by MAPK8 => ECO:0000269|PubMed:21856198, ECO:0007744|PubMed:19690332
ChainResidueDetails
CSER318
BSER64

site_idSWS_FT_FI5
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648
ChainResidueDetails
CSER394
BSER184

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PDB entries from 2024-10-16

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