3EDX

Crystal structure of the W215A/E217A mutant of murine thrombin

Summary for 3EDX

• Entry DOI: 10.2210/pdb3edx/pdb
• Related: 1TQ0 3EE0
• Descriptor: Thrombin light chain, Thrombin heavy chain, SULFATE ION, ... (5 entities in total)
• Functional Keywords: serine protease, acute phase, blood coagulation, cleavage on pair of basic residues, gamma-carboxyglutamic acid, glycoprotein, hydrolase, kringle, protease, zymogen
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 6
• Total formula weight: 106039.64

Authors

Gandhi, P.S.,Page, M.J.,Chen, Z.,Bush-pelc, L.,Di Cera, E. (deposition date: 2008-09-03, release date: 2009-07-07, Last modification date: 2024-11-06)

• Primary citation: Gandhi, P.S.,Page, M.J.,Chen, Z.,Bush-Pelc, L.,Di Cera, E.; Molecular Basis for the Kinetic Differences of the W215A/E217A Mutant of Human and Murine Thrombin; To be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)