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1G7A
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1.2 A structure of T3R3 human insulin at 100 K
分子名称: ACETONE, CHLORIDE ION, GLYCEROL, ...
著者Smith, G.D, Pangborn, W.A, Blessing, R.H.
登録日2000-11-09
公開日2001-08-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Phase changes in T(3)R(3)(f) human insulin: temperature or pressure induced?
Acta Crystallogr.,Sect.D, 57, 2001
2KXK
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BU of 2kxk by Molmil
Human Insulin Mutant A22Gly-B31Lys-B32Arg
分子名称: Insulin A chain, Insulin B chain
著者Bocian, W, Kozerski, L.
登録日2010-05-07
公開日2011-06-01
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Novel recombinant insulin analogue with flexible C - terminus in B chain. NMR structure of biosynthetic engineered A22G-B31K-B32R human insulin monomer in water /acetonitrile solution.
To be Published
2LGB
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Modified A22Gly-B31Arg Human Insulin
分子名称: Insulin A chain, Insulin B chain
著者Bocian, W, Kozerski, L.
登録日2011-07-25
公開日2012-04-11
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Recombinant A22(G)-B31 (R)-human insulin. A22 addition introduces conformational mobility in B chain C-terminus.
J.Biomol.Nmr, 52, 2012
2L1Z
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BU of 2l1z by Molmil
NMR Structure of human insulin mutant GLY-B20-D-ALA, GLY-B23-D-ALA PRO-B28-LYS, LYS-B29-PRO, 20 Structures
分子名称: Insulin A chain, Insulin B chain
著者Wan, Z.L, Hua, Q.X, Huang, K, Hu, S.Q, Philips, N.B, Katsoyannis, J.W, Weiss, M.A.
登録日2010-08-09
公開日2011-08-31
最終更新日2020-02-05
実験手法SOLUTION NMR
主引用文献Chiral Protein Engineering and its Application in G Health
To be Published
2L1Y
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NMR Structure of human insulin mutant GLY-B20-D-ALA, GLY-B23-D-ALA PRO-B28-LYS, LYS-B29-PRO, 20 Structures
分子名称: Insulin A chain, Insulin B chain
著者Wan, Z.L, Hua, Q.X, Huang, K, Hu, S.Q, Philips, N.B, Katsoyannis, J.W, Weiss, M.A.
登録日2010-08-09
公開日2011-08-31
実験手法SOLUTION NMR
主引用文献Chiral Protein Engineering and its Application in G Health
To be Published
2M2N
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BU of 2m2n by Molmil
Structure of [L-HisB24] insulin analogue at pH 8.0
分子名称: Insulin A chain, Insulin B chain
著者Zakova, L, Veverka, V, Jiracek, J.
登録日2012-12-29
公開日2013-03-06
最終更新日2013-06-05
実験手法SOLUTION NMR
主引用文献Structural integrity of the B24 site in human insulin is important for hormone functionality.
J.Biol.Chem., 288, 2013
2M2O
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Structure of [D-HisB24] insulin analogue at pH 1.9
分子名称: Insulin A chain, Insulin B chain
著者Zakova, L, Veverka, V, Jiracek, J.
登録日2012-12-29
公開日2013-03-06
最終更新日2013-06-05
実験手法SOLUTION NMR
主引用文献Structural integrity of the B24 site in human insulin is important for hormone functionality.
J.Biol.Chem., 288, 2013
2LWZ
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NMR Structures of Single-chain Insulin
分子名称: SINGLE-CHAIN INSULIN
著者Weiss, M.A, Yang, Y.
登録日2012-08-09
公開日2013-08-28
実験手法SOLUTION NMR
主引用文献Dynamic repair of an amyloidogenic protein: Insulin fibrillation is blocked by tethering a nascent alpha-helix
To be Published
2M2M
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BU of 2m2m by Molmil
Structure of [L-HisB24] insulin analogue at pH 1.9
分子名称: Insulin A chain, Insulin B chain
著者Zakova, L, Veverka, V, Jiracek, J.
登録日2012-12-28
公開日2013-03-06
最終更新日2013-06-05
実験手法SOLUTION NMR
主引用文献Structural integrity of the B24 site in human insulin is important for hormone functionality.
J.Biol.Chem., 288, 2013
2M1E
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Biosynthetic engineered B28K-B29P human insulin monomer structure in in water solutions.
分子名称: Insulin
著者Bocian, W, Kozerski, L.
登録日2012-11-26
公開日2013-02-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Biosynthetic engineered B28(K)-B29(P) human insulin monomer structure in water and in water/acetonitrile solutions.
J.Biomol.Nmr, 55, 2013
2JMN
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BU of 2jmn by Molmil
NMR structure of human insulin mutant His-B10-Asp, Pro-B28-Lys, Lys-B29-Pro, 20 structures
分子名称: Insulin A chain, Insulin B chain
著者Hua, Q.X, Hu, S.Q, Frank, B.H, Jia, W.H, Chu, Y.C, Wang, S.H, Burke, G.T, Katsoyannis, P.G, Weiss, M.A.
登録日2006-11-21
公開日2006-12-05
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue.
J.Mol.Biol., 264, 1996
2JV1
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BU of 2jv1 by Molmil
NMR structure of human insulin monomer in 35% CD3CN zinc free, 50 structures
分子名称: Insulin
著者Bocian, W, Kozerski, L.
登録日2007-09-11
公開日2007-12-11
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Structure of human insulin monomer in water/acetonitrile solution.
J.Biomol.Nmr, 40, 2008
2JUU
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allo-ThrA3 DKP-insulin
分子名称: Insulin A chain, Insulin B chain
著者Huang, K, Chan, S, Hua, Q, Chu, Y, Wang, R, Klaproth, B, Jia, W, Whittaker, J, De Meyts, P, Nakagawa, S.H, Steiner, D.F, Katsoyannis, P.G, Weiss, M.A.
登録日2007-09-03
公開日2007-10-16
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献The A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor: PHOTO-CROSS-LINKING AND MUTAGENESIS OF A DIABETES-RELATED CREVICE.
J.Biol.Chem., 282, 2007
2N2X
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BU of 2n2x by Molmil
Solution structure of [GlyB24,B27-B29 triazole cross-linked]-insulin analogue at pH 1.9
分子名称: Insulin A chain, Insulin B chain
著者Veverka, V, Hexnerova, R, Jiracek, J.
登録日2015-05-15
公開日2016-02-03
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Rational steering of insulin binding specificity by intra-chain chemical crosslinking.
Sci Rep, 6, 2016
2JUM
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BU of 2jum by Molmil
ThrA3-DKP-insulin
分子名称: Insulin A chain, Insulin B chain
著者Huang, K, Chan, S, Hua, Q, Chu, Y, Wang, R, Klaproth, B, Jia, W, Whittaker, J, De Meyts, P, Nakagawa, S.H, Steiner, D.F, Katsoyannis, P.G, Weiss, M.A.
登録日2007-08-31
公開日2007-10-16
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献The A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor: PHOTO-CROSS-LINKING AND MUTAGENESIS OF A DIABETES-RELATED CREVICE.
J.Biol.Chem., 282, 2007
2N2V
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Solution structure of [B26-B29 triazole cross-linked]-insulin analogue at pH 1.9
分子名称: Insulin A chain, Insulin B chain
著者Veverka, V, Hexnerova, R, Jiracek, J.
登録日2015-05-15
公開日2016-02-03
実験手法SOLUTION NMR
主引用文献Rational steering of insulin binding specificity by intra-chain chemical crosslinking.
Sci Rep, 6, 2016
2MVC
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BU of 2mvc by Molmil
Solution structure of human insulin at pH 1.9
分子名称: Insulin A chain, Insulin B chain
著者Hexnerova, R, Krizkova, K, Maletinska, L, Jiracek, J, Brzozowski, A.M, Zakova, L, Veverka, V.
登録日2014-10-02
公開日2014-12-10
最終更新日2016-06-01
実験手法SOLUTION NMR
主引用文献Structural and Functional Study of the GlnB22-Insulin Mutant Responsible for Maturity-Onset Diabetes of the Young.
Plos One, 9, 2014
2JUV
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AbaA3-DKP-insulin
分子名称: Insulin A chain, Insulin B chain
著者Huang, K, Chan, S, Hua, Q, Chu, Y, Wang, R, Klaproth, B, Jia, W, Whittaker, J, De Meyts, P, Nakagawa, S.H, Steiner, D.F, Katsoyannis, P.G, Weiss, M.A.
登録日2007-09-05
公開日2007-10-16
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献The A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor: PHOTO-CROSS-LINKING AND MUTAGENESIS OF A DIABETES-RELATED CREVICE.
J.Biol.Chem., 282, 2007
2JZQ
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BU of 2jzq by Molmil
Design of an Active Ultra-Stable Single-Chain Insulin Analog 20 Structures
分子名称: Insulin
著者Hua, Q.X, Nakarawa, S, Jia, W.H, Huang, K, Philips, N.F, Hu, S.Q, Weiss, M.A.
登録日2008-01-11
公開日2008-02-26
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Design of an active ultrastable single-chain insulin analog: synthesis, structure, and therapeutic implications.
J.Biol.Chem., 283, 2008
2M2P
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BU of 2m2p by Molmil
Structure of [D-HisB24] insulin analogue at pH 8.0
分子名称: Insulin A chain, Insulin B chain
著者Zakova, L, Veverka, V, Jiracek, J.
登録日2012-12-29
公開日2013-03-06
最終更新日2013-06-05
実験手法SOLUTION NMR
主引用文献Structural integrity of the B24 site in human insulin is important for hormone functionality.
J.Biol.Chem., 288, 2013
2MVD
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BU of 2mvd by Molmil
Solution structure of [GlnB22]-insulin mutant at pH 1.9
分子名称: Insulin A chain, Insulin B chain
著者Hexnerova, R, Krizkova, K, Maletinska, L, Jiracek, J, Brzozowski, A.M, Zakova, L, Veverka, V.
登録日2014-10-02
公開日2014-12-10
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural and Functional Study of the GlnB22-Insulin Mutant Responsible for Maturity-Onset Diabetes of the Young.
Plos One, 9, 2014
2KQQ
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BU of 2kqq by Molmil
NMR structure of human insulin mutant gly-b8-d-ala, his-b10-asp, pro-b28-lys, lys-b29-pro, 20 structures
分子名称: Insulin A chain, Insulin B chain
著者Hua, Q.X, Wan, Z.L, Zhao, M, Jia, W, Huang, K, Weiss, M.A.
登録日2009-11-13
公開日2010-11-24
最終更新日2021-10-13
実験手法SOLUTION NMR
主引用文献Structure and Dynamics of an Turn-Stabilize But Ina Insulin Analog.
To be Published
2KJJ
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Dynamics of insulin probed by 1H-NMR amide proton exchange anomalous flexibility of the receptor-binding surface
分子名称: Insulin
著者Hua, Q.X, Weiss, M.A.
登録日2009-05-29
公開日2010-06-16
最終更新日2021-10-13
実験手法SOLUTION NMR
主引用文献Dynamics of Insulin Probed by 1H-NMR Amide Proton E Anomalous Flexibility of the Receptor-Binding Surfa
To be Published
2K9R
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BU of 2k9r by Molmil
Enhancing the activity of insulin by stereospecific unfolding
分子名称: Insulin
著者Hua, Q.X, Xu, B, Huang, K, Hu, S.Q, Nakarawa, S, Jia, W.H, Philips, N.F.P, Wittaker, L, Wittaker, J, Katsoyannis, P.G, Weiss, M.A.
登録日2008-10-23
公開日2008-11-11
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Enhancing the Activity of a Protein by Stereospecific Unfolding: CONFORMATIONAL LIFE CYCLE OF INSULIN AND ITS EVOLUTIONARY ORIGINS.
J.Biol.Chem., 284, 2009
2K91
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Enhancing the activity of insulin by stereospecific unfolding
分子名称: Insulin
著者Hua, Q.X, Xu, B, Huang, K, Hu, S.Q, Nakarawa, S, Jia, W.H, Philips, N.F.P, Wittaker, L, Wittaker, J, Katsoyannis, P.G, Weiss, M.A.
登録日2008-09-29
公開日2008-11-18
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Enhancing the Activity of a Protein by Stereospecific Unfolding: CONFORMATIONAL LIFE CYCLE OF INSULIN AND ITS EVOLUTIONARY ORIGINS.
J.Biol.Chem., 284, 2009

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