2LGB

Modified A22Gly-B31Arg Human Insulin

Summary for 2LGB

• Entry DOI: 10.2210/pdb2lgb/pdb
• NMR Information: BMRB: 17803
• Descriptor: Insulin A chain, Insulin B chain (2 entities in total)
• Functional Keywords: hormone
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P01308 P01308
• Total number of polymer chains: 2
• Total formula weight: 6031.90

Authors

Bocian, W.,Kozerski, L. (deposition date: 2011-07-25, release date: 2012-04-11, Last modification date: 2023-06-14)

• Primary citation: Borowicz, P.,Bednarek, E.,Bocian, W.,Sitkowski, J.,Jaworska, B.,Mikolajczyk, J.,Glabski, T.,Stadnik, D.,Surmacz, W.,Bogiel, M.,Kozerski, L.; Recombinant A22(G)-B31 (R)-human insulin. A22 addition introduces conformational mobility in B chain C-terminus.; J.Biomol.Nmr, 52:365-370, 2012; PubMed: 22350952; DOI: 10.1007/s10858-012-9612-y

Experimental method

SOLUTION NMR