2LGB

Modified A22Gly-B31Arg Human Insulin

Summary for 2LGB

DescriptorInsulin A chain, Insulin B chain (2 entities in total)
Functional Keywordshormone
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains2
Total molecular weight6031.9
Authors
Bocian, W.,Kozerski, L. (deposition date: 2011-07-25, release date: 2012-04-11, Last modification date: 2012-07-04)
Primary citation
Borowicz, P.,Bednarek, E.,Bocian, W.,Sitkowski, J.,Jaworska, B.,Mikolajczyk, J.,Glabski, T.,Stadnik, D.,Surmacz, W.,Bogiel, M.,Kozerski, L.
Recombinant A22(G)-B31 (R)-human insulin. A22 addition introduces conformational mobility in B chain C-terminus.
J.Biomol.Nmr, 52:365-370, 2012
PubMed: 22350952 (PDB entries with the same primary citation)
DOI: 10.1007/s10858-012-9612-y
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers00.6%4.2%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation reportDownload