2MVD

Solution structure of [GlnB22]-insulin mutant at pH 1.9

Summary for 2MVD

Related2MVC
DescriptorInsulin A chain, Insulin B chain (2 entities in total)
Functional Keywordsinsulin, mody, hormone
Biological sourceHomo sapiens (Human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains2
Total molecular weight5788.59
Authors
Hexnerova, R.,Krizkova, K.,Maletinska, L.,Jiracek, J.,Brzozowski, A.M.,Zakova, L.,Veverka, V. (deposition date: 2014-10-02, release date: 2014-12-10)
Primary citation
Krizkova, K.,Veverka, V.,Maletinska, L.,Hexnerova, R.,Brzozowski, A.M.,Jiracek, J.,Zakova, L.
Structural and Functional Study of the GlnB22-Insulin Mutant Responsible for Maturity-Onset Diabetes of the Young.
Plos One, 9:e112883-e112883, 2014
PubMed: 25423173 (PDB entries with the same primary citation)
DOI: 10.1371/journal.pone.0112883
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers01.4%6.8%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures