2N2X
Solution structure of [GlyB24,B27-B29 triazole cross-linked]-insulin analogue at pH 1.9
Summary for 2N2X
Entry DOI | 10.2210/pdb2n2x/pdb |
Related | 2N2V 2N2W |
NMR Information | BMRB: 25615 |
Descriptor | Insulin A chain, Insulin B chain (2 entities in total) |
Functional Keywords | hormone |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P01308 P01308 |
Total number of polymer chains | 2 |
Total formula weight | 5734.50 |
Authors | Veverka, V.,Hexnerova, R.,Jiracek, J. (deposition date: 2015-05-15, release date: 2016-02-03, Last modification date: 2023-12-27) |
Primary citation | Vikova, J.,Collinsova, M.,Kletvikova, E.,Budesinsky, M.,Kaplan, V.,Zakova, L.,Veverka, V.,Hexnerova, R.,Avino, R.J.,Strakova, J.,Selicharova, I.,Vanek, V.,Wright, D.W.,Watson, C.J.,Turkenburg, J.P.,Brzozowski, A.M.,Jiracek, J. Rational steering of insulin binding specificity by intra-chain chemical crosslinking. Sci Rep, 6:19431-19431, 2016 Cited by PubMed: 26792393DOI: 10.1038/srep19431 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report