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PDB: 280 件

6EYD
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Structure of Mycobacterium smegmatis RNA polymerase Sigma-A holoenzyme
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Kouba, T, Barvik, I, Krasny, L.
登録日2017-11-11
公開日2018-12-12
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.22 Å)
主引用文献The Core and Holoenzyme Forms of RNA Polymerase fromMycobacterium smegmatis.
J. Bacteriol., 201, 2019
8FTD
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Structure of Escherichia coli CedA in complex with transcription initiation complex
分子名称: CHAPSO, Cell division activator CedA, DNA-directed RNA polymerase subunit alpha, ...
著者Liu, M, Vassyliev, N, Nudler, E.
登録日2023-01-11
公開日2024-01-10
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献General transcription factor from Escherichia coli with a distinct mechanism of action.
Nat.Struct.Mol.Biol., 31, 2024
6FBV
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Single particle cryo em structure of Mycobacterium tuberculosis RNA polymerase in complex with Fidaxomicin
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Das, K, Lin, W, Ebright, E.
登録日2017-12-19
公開日2018-02-28
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3).
Mol. Cell, 70, 2018
5D4D
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Crystal structure of Thermus thermophilus product complex for transcription initiation with NAD and CTP
分子名称: ADENOSINE MONOPHOSPHATE, CYTIDINE-5'-MONOPHOSPHATE, CYTIDINE-5'-TRIPHOSPHATE, ...
著者Zhang, Y, Ebright, R.H.
登録日2015-08-07
公開日2016-07-06
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA.
Nature, 535, 2016
8GZH
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Cryo-EM structure of Synechocystis sp. PCC 6803 CTP-bound RPitc
分子名称: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者You, L.L, Shen, L.Q, Zhang, Y.
登録日2022-09-27
公開日2023-04-19
実験手法ELECTRON MICROSCOPY (2.96 Å)
主引用文献Cryo-EM structure of Synechocystis sp. PCC 6803 CTP-bound RPitc
Proc.Natl.Acad.Sci.USA, 2023
8GZG
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Cryo-EM structure of Synechocystis sp. PCC 6803 RPitc
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Shen, L.Q, You, L.L, Zhang, Y.
登録日2022-09-27
公開日2023-04-19
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Cryo-EM structure of Synechocystis sp. PCC 6803 CTP-bound RPitc
Proc.Natl.Acad.Sci.USA, 2023
7U22
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Mycobacterium tuberculosis RNA polymerase sigma A holoenzyme open promoter complex containing UMN-7
分子名称: (9S,14S,15R,16S,17R,18R,19R,20S,21S,25R)-5,6,18,20-tetrahydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-(2-methylpropyl)-10,26-dioxo-1,3,9,10-tetrahydrospiro[9,4-(epoxypentadecanoimino)furo[2',3':7,8]naphtho[1,2-d]imidazole-2,4'-piperidin]-16-yl benzoate, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Molodtsov, V, Ebright, R.H.
登録日2022-02-22
公開日2022-10-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.87 Å)
主引用文献Redesign of Rifamycin Antibiotics to Overcome ADP-Ribosylation-Mediated Resistance.
Angew.Chem.Int.Ed.Engl., 61, 2022
5D4E
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Crystal structure of Thermus thermophilus product complex for transcription initiation with 3'-dephosphate-CoA and CTP
分子名称: CYTIDINE-5'-MONOPHOSPHATE, DEPHOSPHO COENZYME A, DIPHOSPHATE, ...
著者Zhang, Y, Ebright, R.H.
登録日2015-08-07
公開日2016-07-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA.
Nature, 535, 2016
5E18
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T. thermophilus transcription initiation complex having a YYY discriminator sequence and a nontemplate-strand length corresponding to TSS selection at position 8 (RPo-CCC-8)
分子名称: DNA (28-MER), DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Zhang, Y, Ebright, R.H.
登録日2015-09-29
公開日2016-03-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Multiplexed protein-DNA cross-linking: Scrunching in transcription start site selection.
Science, 351, 2016
7UBM
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Transcription antitermination complex: "pre-engaged" Qlambda-loading complex
分子名称: Antitermination protein Q, DNA (52-MER), DNA (53-MER), ...
著者Yin, Z, Ebright, R.H.
登録日2022-03-15
公開日2022-09-28
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献In transcription antitermination by Q lambda , NusA induces refolding of Q lambda to form a nozzle that extends the RNA polymerase RNA-exit channel.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UBN
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BU of 7ubn by Molmil
Transcription antitermination complex: NusA-containing "engaged" Qlambda-loading complex
分子名称: Antitermination protein, DNA (52-MER), DNA (53-MER), ...
著者Yin, Z, Ebright, R.H.
登録日2022-03-15
公開日2022-09-28
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献In transcription antitermination by Q lambda , NusA induces refolding of Q lambda to form a nozzle that extends the RNA polymerase RNA-exit channel.
Proc.Natl.Acad.Sci.USA, 119, 2022
1L0O
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BU of 1l0o by Molmil
Crystal Structure of the Bacillus stearothermophilus Anti-Sigma Factor SpoIIAB with the Sporulation Sigma Factor SigmaF
分子名称: ADENOSINE-5'-DIPHOSPHATE, Anti-sigma F factor, MAGNESIUM ION, ...
著者Campbell, E.A, Masuda, S, Sun, J.L, Muzzin, O, Olson, C.A, Wang, S, Darst, S.A.
登録日2002-02-12
公開日2002-04-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the Bacillus stearothermophilus anti-sigma factor SpoIIAB with the sporulation sigma factor sigmaF.
Cell(Cambridge,Mass.), 108, 2002
1L9U
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THERMUS AQUATICUS RNA POLYMERASE HOLOENZYME AT 4 A RESOLUTION
分子名称: MAGNESIUM ION, RNA POLYMERASE, ALPHA SUBUNIT, ...
著者Murakami, K.S, Masuda, S, Darst, S.A.
登録日2002-03-26
公開日2002-05-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structural basis of transcription initiation: RNA polymerase holoenzyme at 4 A resolution.
Science, 296, 2002
5E17
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T. thermophilus transcription initiation complex having a RRR discriminator sequence and a nontemplate-strand length corresponding to TSS selection at position 7 (RPo-GGG-7)
分子名称: DNA (27-MER), DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Zhang, Y, Ebright, R.H.
登録日2015-09-29
公開日2016-03-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Multiplexed protein-DNA cross-linking: Scrunching in transcription start site selection.
Science, 351, 2016
1KU2
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BU of 1ku2 by Molmil
Crystal Structure of Thermus aquaticus RNA Polymerase Sigma Subunit Fragment Containing Regions 1.2 to 3.1
分子名称: SULFATE ION, sigma factor sigA
著者Campbell, E.A, Muzzin, O, Chlenov, M, Sun, J.L, Olson, C.A, Weinman, O, Trester-Zedlitz, M.L, Darst, S.A.
登録日2002-01-21
公開日2002-04-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of the bacterial RNA polymerase promoter specificity sigma subunit.
Mol.Cell, 9, 2002
5D4C
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BU of 5d4c by Molmil
Crystal structure of Thermus thermophilus product complex for transcription initiation with ATP and CTP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYTIDINE-5'-MONOPHOSPHATE, CYTIDINE-5'-TRIPHOSPHATE, ...
著者Zhang, Y, Ebright, R.H.
登録日2015-08-07
公開日2016-07-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.28 Å)
主引用文献The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA.
Nature, 535, 2016
8HIH
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BU of 8hih by Molmil
Cryo-EM structure of Mycobacterium tuberculosis transcription initiation complex with transcription factor GlnR
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Lin, W, Shi, J, Xu, J.C.
登録日2022-11-20
公開日2023-06-07
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献Structural insights into the transcription activation mechanism of the global regulator GlnR from actinobacteria.
Proc.Natl.Acad.Sci.USA, 120, 2023
8H40
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Cryo-EM structure of the transcription activation complex NtcA-TAC
分子名称: DNA (125-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Han, S.J, Jiang, Y.L, You, L.L, Shen, L.Q, Wu, X.X, Yang, F, Kong, W.W, Chen, Z.P, Zhang, Y, Zhou, C.Z.
登録日2022-10-09
公開日2023-10-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献DNA looping mediates cooperative transcription activation.
Nat.Struct.Mol.Biol., 31, 2024
1ZYR
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BU of 1zyr by Molmil
Structure of Thermus thermophilus RNA polymerase holoenzyme in complex with the antibiotic streptolydigin
分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase omega chain, ...
著者Tuske, S, Sarafianos, S.G, Wang, X, Hudson, B, Sineva, E, Mukhopadhyay, J, Birktoft, J.J, Leroy, O, Ismail, S, Clark, A.D, Dharia, C, Napoli, A, Laptenko, O, Lee, J, Borukhov, S, Ebright, R.H, Arnold, E.
登録日2005-06-10
公開日2005-09-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation.
Cell(Cambridge,Mass.), 122, 2005
1L9Z
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BU of 1l9z by Molmil
Thermus aquaticus RNA Polymerase Holoenzyme/Fork-Junction Promoter DNA Complex at 6.5 A Resolution
分子名称: MAGNESIUM ION, RNA POLYMERASE, ALPHA SUBUNIT, ...
著者Murakami, K.S, Masuda, S, Campbell, E.A, Muzzin, O, Darst, S.A.
登録日2002-03-27
公開日2002-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (6.5 Å)
主引用文献Structural basis of transcription initiation: an RNA polymerase holoenzyme-DNA complex.
Science, 296, 2002
2A6E
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BU of 2a6e by Molmil
Crystal structure of the T. Thermophilus RNA polymerase holoenzyme
分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
著者Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-07-02
公開日2005-09-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins.
Cell(Cambridge,Mass.), 122, 2005
2A6H
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Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic sterptolydigin
分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
著者Temiakov, D, Zenkin, N, Vassylyeva, M.N, Perederina, A, Tahirov, T.H, Savkina, M, Zorov, S, Nikiforov, V, Igarashi, N, Matsugaki, N, Wakatsuki, S, Severinov, K, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-07-02
公開日2005-09-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of transcription inhibition by antibiotic streptolydigin.
Mol.Cell, 19, 2005
2A69
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Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic rifapentin
分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
著者Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-07-02
公開日2005-09-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins.
Cell(Cambridge,Mass.), 122, 2005
2A68
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Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic rifabutin
分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
著者Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-07-01
公開日2005-09-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins.
Cell(Cambridge,Mass.), 122, 2005
1IW7
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BU of 1iw7 by Molmil
Crystal structure of the RNA polymerase holoenzyme from Thermus thermophilus at 2.6A resolution
分子名称: LEAD (II) ION, MAGNESIUM ION, RNA polymerase alpha subunit, ...
著者RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2002-04-22
公開日2002-06-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of a bacterial RNA polymerase holoenzyme at 2.6 A resolution
NATURE, 417, 2002

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