6EYD
| Structure of Mycobacterium smegmatis RNA polymerase Sigma-A holoenzyme | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Kouba, T, Barvik, I, Krasny, L. | 登録日 | 2017-11-11 | 公開日 | 2018-12-12 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.22 Å) | 主引用文献 | The Core and Holoenzyme Forms of RNA Polymerase fromMycobacterium smegmatis. J. Bacteriol., 201, 2019
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8FTD
| Structure of Escherichia coli CedA in complex with transcription initiation complex | 分子名称: | CHAPSO, Cell division activator CedA, DNA-directed RNA polymerase subunit alpha, ... | 著者 | Liu, M, Vassyliev, N, Nudler, E. | 登録日 | 2023-01-11 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | General transcription factor from Escherichia coli with a distinct mechanism of action. Nat.Struct.Mol.Biol., 31, 2024
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6FBV
| Single particle cryo em structure of Mycobacterium tuberculosis RNA polymerase in complex with Fidaxomicin | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Das, K, Lin, W, Ebright, E. | 登録日 | 2017-12-19 | 公開日 | 2018-02-28 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | 主引用文献 | Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3). Mol. Cell, 70, 2018
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5D4D
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8GZH
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8GZG
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7U22
| Mycobacterium tuberculosis RNA polymerase sigma A holoenzyme open promoter complex containing UMN-7 | 分子名称: | (9S,14S,15R,16S,17R,18R,19R,20S,21S,25R)-5,6,18,20-tetrahydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-(2-methylpropyl)-10,26-dioxo-1,3,9,10-tetrahydrospiro[9,4-(epoxypentadecanoimino)furo[2',3':7,8]naphtho[1,2-d]imidazole-2,4'-piperidin]-16-yl benzoate, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Molodtsov, V, Ebright, R.H. | 登録日 | 2022-02-22 | 公開日 | 2022-10-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.87 Å) | 主引用文献 | Redesign of Rifamycin Antibiotics to Overcome ADP-Ribosylation-Mediated Resistance. Angew.Chem.Int.Ed.Engl., 61, 2022
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5D4E
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5E18
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7UBM
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7UBN
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1L0O
| Crystal Structure of the Bacillus stearothermophilus Anti-Sigma Factor SpoIIAB with the Sporulation Sigma Factor SigmaF | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Anti-sigma F factor, MAGNESIUM ION, ... | 著者 | Campbell, E.A, Masuda, S, Sun, J.L, Muzzin, O, Olson, C.A, Wang, S, Darst, S.A. | 登録日 | 2002-02-12 | 公開日 | 2002-04-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of the Bacillus stearothermophilus anti-sigma factor SpoIIAB with the sporulation sigma factor sigmaF. Cell(Cambridge,Mass.), 108, 2002
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1L9U
| THERMUS AQUATICUS RNA POLYMERASE HOLOENZYME AT 4 A RESOLUTION | 分子名称: | MAGNESIUM ION, RNA POLYMERASE, ALPHA SUBUNIT, ... | 著者 | Murakami, K.S, Masuda, S, Darst, S.A. | 登録日 | 2002-03-26 | 公開日 | 2002-05-22 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Structural basis of transcription initiation: RNA polymerase holoenzyme at 4 A resolution. Science, 296, 2002
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5E17
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1KU2
| Crystal Structure of Thermus aquaticus RNA Polymerase Sigma Subunit Fragment Containing Regions 1.2 to 3.1 | 分子名称: | SULFATE ION, sigma factor sigA | 著者 | Campbell, E.A, Muzzin, O, Chlenov, M, Sun, J.L, Olson, C.A, Weinman, O, Trester-Zedlitz, M.L, Darst, S.A. | 登録日 | 2002-01-21 | 公開日 | 2002-04-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of the bacterial RNA polymerase promoter specificity sigma subunit. Mol.Cell, 9, 2002
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5D4C
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8HIH
| Cryo-EM structure of Mycobacterium tuberculosis transcription initiation complex with transcription factor GlnR | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Lin, W, Shi, J, Xu, J.C. | 登録日 | 2022-11-20 | 公開日 | 2023-06-07 | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | 主引用文献 | Structural insights into the transcription activation mechanism of the global regulator GlnR from actinobacteria. Proc.Natl.Acad.Sci.USA, 120, 2023
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8H40
| Cryo-EM structure of the transcription activation complex NtcA-TAC | 分子名称: | DNA (125-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Han, S.J, Jiang, Y.L, You, L.L, Shen, L.Q, Wu, X.X, Yang, F, Kong, W.W, Chen, Z.P, Zhang, Y, Zhou, C.Z. | 登録日 | 2022-10-09 | 公開日 | 2023-10-04 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | DNA looping mediates cooperative transcription activation. Nat.Struct.Mol.Biol., 31, 2024
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1ZYR
| Structure of Thermus thermophilus RNA polymerase holoenzyme in complex with the antibiotic streptolydigin | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase omega chain, ... | 著者 | Tuske, S, Sarafianos, S.G, Wang, X, Hudson, B, Sineva, E, Mukhopadhyay, J, Birktoft, J.J, Leroy, O, Ismail, S, Clark, A.D, Dharia, C, Napoli, A, Laptenko, O, Lee, J, Borukhov, S, Ebright, R.H, Arnold, E. | 登録日 | 2005-06-10 | 公開日 | 2005-09-13 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation. Cell(Cambridge,Mass.), 122, 2005
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1L9Z
| Thermus aquaticus RNA Polymerase Holoenzyme/Fork-Junction Promoter DNA Complex at 6.5 A Resolution | 分子名称: | MAGNESIUM ION, RNA POLYMERASE, ALPHA SUBUNIT, ... | 著者 | Murakami, K.S, Masuda, S, Campbell, E.A, Muzzin, O, Darst, S.A. | 登録日 | 2002-03-27 | 公開日 | 2002-05-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (6.5 Å) | 主引用文献 | Structural basis of transcription initiation: an RNA polymerase holoenzyme-DNA complex. Science, 296, 2002
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2A6E
| Crystal structure of the T. Thermophilus RNA polymerase holoenzyme | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | 著者 | Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-07-02 | 公開日 | 2005-09-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
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2A6H
| Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic sterptolydigin | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | 著者 | Temiakov, D, Zenkin, N, Vassylyeva, M.N, Perederina, A, Tahirov, T.H, Savkina, M, Zorov, S, Nikiforov, V, Igarashi, N, Matsugaki, N, Wakatsuki, S, Severinov, K, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-07-02 | 公開日 | 2005-09-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis of transcription inhibition by antibiotic streptolydigin. Mol.Cell, 19, 2005
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2A69
| Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic rifapentin | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | 著者 | Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-07-02 | 公開日 | 2005-09-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
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2A68
| Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic rifabutin | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | 著者 | Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-07-01 | 公開日 | 2005-09-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
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1IW7
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