8HVR

Cryo-EM structure of AfsR-dependent transcription activation complex with afsS promoter

Summary for 8HVR

• Entry DOI: 10.2210/pdb8hvr/pdb
• EMDB information: 35047
• Descriptor: DNA-directed RNA polymerase subunit alpha, DNA (65-MER), MAGNESIUM ION, ... (12 entities in total)
• Functional Keywords: rna polymerase, sarp regulator, gene regulation, transcription
• Biological source: Streptomyces coelicolor A3(2); More
• Total number of polymer chains: 13
• Total formula weight: 587733.18

Authors

Wang, Y.,Zheng, J. (deposition date: 2022-12-27, release date: 2023-12-27, Last modification date: 2024-04-03)

• Primary citation: Wang, Y.,Yang, X.,Yu, F.,Deng, Z.,Lin, S.,Zheng, J.; Structural and functional characterization of AfsR, an SARP family transcriptional activator of antibiotic biosynthesis in Streptomyces.; Plos Biol., 22:e3002528-e3002528, 2024; PubMed: 38427710; DOI: 10.1371/journal.pbio.3002528

Experimental method

ELECTRON MICROSCOPY (3.35 Å)