5E18
T. thermophilus transcription initiation complex having a YYY discriminator sequence and a nontemplate-strand length corresponding to TSS selection at position 8 (RPo-CCC-8)
Summary for 5E18
Entry DOI | 10.2210/pdb5e18/pdb |
Related | 5E17 |
Descriptor | DNA-directed RNA polymerase subunit alpha, ZINC ION, DNA-directed RNA polymerase subunit beta, ... (11 entities in total) |
Functional Keywords | dna, single-stranded, dna-directed rna polymerases, gene expression regulation, bacterial, promoter regions, protein conformation, sigma factor, thermus thermophilus, transcription initiation, discriminator, consensus, rna, abortive, sigma, transcription start site, scrunching, transcription-dna-rna complex, transcription/dna/rna |
Biological source | Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) More |
Cellular location | Cytoplasm : Q5SKW1 |
Total number of polymer chains | 9 |
Total formula weight | 446344.09 |
Authors | Zhang, Y.,Ebright, R.H. (deposition date: 2015-09-29, release date: 2016-03-09, Last modification date: 2023-09-27) |
Primary citation | Winkelman, J.T.,Vvedenskaya, I.O.,Zhang, Y.,Zhang, Y.,Bird, J.G.,Taylor, D.M.,Gourse, R.L.,Ebright, R.H.,Nickels, B.E. Multiplexed protein-DNA cross-linking: Scrunching in transcription start site selection. Science, 351:1090-1093, 2016 Cited by PubMed: 26941320DOI: 10.1126/science.aad6881 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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