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5D4E

Crystal structure of Thermus thermophilus product complex for transcription initiation with 3'-dephosphate-CoA and CTP

Summary for 5D4E
Entry DOI10.2210/pdb5d4e/pdb
Related4G7H 5D4C 5D4D
DescriptorDNA-directed RNA polymerase subunit alpha, CYTIDINE-5'-MONOPHOSPHATE, DIPHOSPHATE, ... (13 entities in total)
Functional Keywordscoenzyme a, rna polymerase, transcription initiation, bacterial, ncin, non-canonical initiating nucleotide, 3'-dephosphate-coenzyme a, primer-dependent initiation, dna, single-stranded, dna-directed rna polymerases, gene expression regulation, promoter regions, genetic, protein conformation, sigma factor, transcription-dna complex, transcription/dna
Biological sourceThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
More
Cellular locationCytoplasm : Q72L95
Total number of polymer chains16
Total formula weight889082.15
Authors
Zhang, Y.,Ebright, R.H. (deposition date: 2015-08-07, release date: 2016-07-06, Last modification date: 2023-09-27)
Primary citationBird, J.G.,Zhang, Y.,Tian, Y.,Panova, N.,Barvik, I.,Greene, L.,Liu, M.,Buckley, B.,Krasny, L.,Lee, J.K.,Kaplan, C.D.,Ebright, R.H.,Nickels, B.E.
The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA.
Nature, 535:444-447, 2016
Cited by
PubMed: 27383794
DOI: 10.1038/nature18622
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.08 Å)
Structure validation

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