5D4E
Crystal structure of Thermus thermophilus product complex for transcription initiation with 3'-dephosphate-CoA and CTP
Summary for 5D4E
Entry DOI | 10.2210/pdb5d4e/pdb |
Related | 4G7H 5D4C 5D4D |
Descriptor | DNA-directed RNA polymerase subunit alpha, CYTIDINE-5'-MONOPHOSPHATE, DIPHOSPHATE, ... (13 entities in total) |
Functional Keywords | coenzyme a, rna polymerase, transcription initiation, bacterial, ncin, non-canonical initiating nucleotide, 3'-dephosphate-coenzyme a, primer-dependent initiation, dna, single-stranded, dna-directed rna polymerases, gene expression regulation, promoter regions, genetic, protein conformation, sigma factor, transcription-dna complex, transcription/dna |
Biological source | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) More |
Cellular location | Cytoplasm : Q72L95 |
Total number of polymer chains | 16 |
Total formula weight | 889082.15 |
Authors | Zhang, Y.,Ebright, R.H. (deposition date: 2015-08-07, release date: 2016-07-06, Last modification date: 2023-09-27) |
Primary citation | Bird, J.G.,Zhang, Y.,Tian, Y.,Panova, N.,Barvik, I.,Greene, L.,Liu, M.,Buckley, B.,Krasny, L.,Lee, J.K.,Kaplan, C.D.,Ebright, R.H.,Nickels, B.E. The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA. Nature, 535:444-447, 2016 Cited by PubMed: 27383794DOI: 10.1038/nature18622 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.08 Å) |
Structure validation
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