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PDB: 1507 件
1S1Q
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BU of 1s1q by Molmil
TSG101(UEV) domain in complex with Ubiquitin
分子名称: ACETIC ACID, COPPER (II) ION, SULFATE ION, ...
著者Sundquist, W.I, Schubert, H.L, Kelly, B.N, Hill, G.C, Holton, J.M, Hill, C.P.
登録日2004-01-07
公開日2004-05-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Ubiquitin recognition by the human TSG101 protein
Mol.Cell, 13, 2004
4JQW
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BU of 4jqw by Molmil
Crystal Structure of a Complex of NOD1 CARD and Ubiquitin
分子名称: Nucleotide-binding oligomerization domain-containing protein 1, PHOSPHATE ION, Polyubiquitin-C
著者Ver Heul, A.M, Gakhar, L, Piper, R.C, Ramaswamy, S.
登録日2013-03-20
公開日2014-03-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of a complex of NOD1 CARD and ubiquitin
Plos One, 9, 2014
4JIO
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BU of 4jio by Molmil
Bro1 V domain and ubiquitin
分子名称: BRO1, Ubiquitin
著者Pashkova, N, Gakhar, L, Piper, R.C.
登録日2013-03-06
公開日2013-06-19
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献The yeast alix homolog bro1 functions as a ubiquitin receptor for protein sorting into multivesicular endosomes.
Dev.Cell, 25, 2013
4I6L
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BU of 4i6l by Molmil
Crystal structure of OTUB1 in complex with ubiquitin variant
分子名称: Ubiquitin, Ubiquitin thioesterase OTUB1
著者Juang, Y.C, Sicheri, F.
登録日2012-11-29
公開日2013-01-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.488 Å)
主引用文献A strategy for modulation of enzymes in the ubiquitin system.
Science, 339, 2013
1VCB
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BU of 1vcb by Molmil
THE VHL-ELONGINC-ELONGINB STRUCTURE
分子名称: PROTEIN (ELONGIN B), PROTEIN (ELONGIN C), PROTEIN (VHL)
著者Stebbins, C.E, Kaelin, W.G, Pavletich, N.P.
登録日1999-03-13
公開日1999-04-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function.
Science, 284, 1999
4K1R
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BU of 4k1r by Molmil
Crystal structure of Schizosaccharomyces pombe sst2 catalytic domain and Ubiquitin
分子名称: 1,2-ETHANEDIOL, AMSH-like protease sst2, CHLORIDE ION, ...
著者Shrestha, R.K, Das, C.
登録日2013-04-05
公開日2014-04-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.632 Å)
主引用文献Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product.
Biochemistry, 53, 2014
4KSK
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BU of 4ksk by Molmil
Gumby/Fam105B in complex with ubiquitin
分子名称: Polyubiquitin-C, Protein FAM105B, SULFATE ION
著者Ceccarelli, D.F, Juang, Y.-C, Sicheri, F.
登録日2013-05-17
公開日2013-06-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis.
Nature, 498, 2013
4KSL
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BU of 4ksl by Molmil
Gumby/Fam105B in complex with linear di-ubiquitin
分子名称: Polyubiquitin-C, Protein FAM105B
著者Juang, Y.-C, Ceccarelli, D.F, Sicheri, F.
登録日2013-05-17
公開日2013-06-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis.
Nature, 498, 2013
4K95
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BU of 4k95 by Molmil
Crystal Structure of Parkin
分子名称: E3 ubiquitin-protein ligase parkin, ZINC ION
著者Seirafi, M, Menade, M, Sauve, V, Kozlov, G, Trempe, J.-F, Nagar, B, Gehring, K.
登録日2013-04-19
公開日2013-05-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (6.499 Å)
主引用文献Structure of parkin reveals mechanisms for ubiquitin ligase activation.
Science, 340, 2013
4II3
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BU of 4ii3 by Molmil
Crystal structure of S. pombe Ubiquitin activating enzyme 1 (Uba1) in complex with ubiquitin and ATP/Mg
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ...
著者Olsen, S.K, Lima, C.D.
登録日2012-12-19
公開日2013-02-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of a ubiquitin E1-E2 complex: insights to E1-E2 thioester transfer.
Mol.Cell, 49, 2013
4IUM
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BU of 4ium by Molmil
Equine arteritis virus papain-like protease 2 (PLP2) covalently bound to ubiquitin
分子名称: GLYCEROL, Ubiquitin, ZINC ION, ...
著者Bailey-Elkin, B.A, James, T.W, Mark, B.L.
登録日2013-01-21
公開日2013-02-13
最終更新日2013-03-20
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Deubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cells.
Proc.Natl.Acad.Sci.USA, 110, 2013
4LJO
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BU of 4ljo by Molmil
Structure of an active ligase (HOIP)/ubiquitin transfer complex
分子名称: E3 ubiquitin-protein ligase RNF31, IMIDAZOLE, Polyubiquitin-C, ...
著者Rana, R.R, Stieglitz, B, Koliopoulos, M.G, Morris-Davies, A.C, Christodoulou, E, Howell, S, Brown, N.R, Rittinger, K.
登録日2013-07-05
公開日2013-10-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.564 Å)
主引用文献Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP.
Nature, 503, 2013
7NPI
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BU of 7npi by Molmil
Crystal structure of Mindy2 (C266A) in complex with Lys48-linked penta-ubiquitin (K48-Ub5)
分子名称: CHLORIDE ION, Polyubiquitin-C, SODIUM ION, ...
著者Lange, S.M, Armstrong, L.A, Kulathu, Y.
登録日2021-02-26
公開日2021-09-15
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2.
Mol.Cell, 81, 2021
7O2W
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BU of 7o2w by Molmil
Structure of the C9orf72-SMCR8 complex
分子名称: Guanine nucleotide exchange protein SMCR8,Guanine nucleotide exchange protein SMCR8,Maltose/maltodextrin-binding periplasmic protein, Ubiquitin-like protein SMT3,Guanine nucleotide exchange C9orf72
著者Noerpel, J, Cavadini, S, Schenk, A.D, Graff-Meyer, A, Chao, J, Bhaskar, V.
登録日2021-03-31
公開日2021-07-21
最終更新日2022-02-02
実験手法ELECTRON MICROSCOPY
主引用文献Structure of the human C9orf72-SMCR8 complex reveals a multivalent protein interaction architecture.
Plos Biol., 19, 2021
7OJE
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BU of 7oje by Molmil
Crystal structure of the covalent complex between Tribolium castaneum deubiquitinase ZUP and Ubiquitin-PA
分子名称: 1,2-ETHANEDIOL, CITRIC ACID, Lys-63-specific deubiquitinase ZUFSP, ...
著者Pichlo, C, Hermanns, T, Hofmann, K, Baumann, U.
登録日2021-05-14
公開日2022-02-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A structural basis for the diverse linkage specificities within the ZUFSP deubiquitinase family.
Nat Commun, 13, 2022
5HPS
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BU of 5hps by Molmil
System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: WWP1 and UbV P1.1
分子名称: Ubiquitin variant P1.1, WWP1 HECT
著者Wu, K.-P, Mercredi, P.Y, Schulman, B.A.
登録日2016-01-20
公開日2016-03-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
5HPK
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BU of 5hpk by Molmil
System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: NEDD4L and UbV NL.1
分子名称: E3 ubiquitin-protein ligase NEDD4-like, Ubiquitin variant NL.1
著者Wu, K.-P, Mukherjee, M, Mercredi, P.Y, Schulman, B.A.
登録日2016-01-20
公開日2016-03-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.431 Å)
主引用文献System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
7OWD
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BU of 7owd by Molmil
Structure of CYLD CAP-Gly3 (467-552) bound to Ub; tetragonal space group
分子名称: Ubiquitin, Ubiquitin carboxyl-terminal hydrolase CYLD
著者Elliott, P.R, Komander, D.
登録日2021-06-17
公開日2021-10-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains.
Cell Rep, 37, 2021
7OWC
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BU of 7owc by Molmil
Structure of CYLD CAP-Gly3 (467-565) bound to Ub; orthorhobic space group
分子名称: Deubiquitinating enzyme CYLD, Ubiquitin-60S ribosomal protein L40
著者Elliott, P.R, Komander, D.
登録日2021-06-17
公開日2021-10-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains.
Cell Rep, 37, 2021
5HPL
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BU of 5hpl by Molmil
System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: Rsp5 and UbV R5.4
分子名称: Rsp5, Ubiquitin variant R5.4
著者Wu, K.-P, Kamadurai, H.B, Schulman, B.A.
登録日2016-01-20
公開日2016-03-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
3O65
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BU of 3o65 by Molmil
Crystal structure of a Josephin-ubiquitin complex: Evolutionary restraints on ataxin-3 deubiquitinating activity
分子名称: Putative ataxin-3-like protein, SODIUM ION, Ubiquitin
著者Weeks, S.D, Grasty, K.C, Hernandez-Cuebas, L, Loll, P.J.
登録日2010-07-28
公開日2010-11-24
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of a Josephin-Ubiquitin Complex: EVOLUTIONARY RESTRAINTS ON ATAXIN-3 DEUBIQUITINATING ACTIVITY.
J.Biol.Chem., 286, 2011
3OFI
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BU of 3ofi by Molmil
Crystal structure of human insulin-degrading enzyme in complex with ubiquitin
分子名称: 1,4-DIETHYLENE DIOXIDE, Insulin-degrading enzyme, Ubiquitin, ...
著者Kalas, V, Ralat, L.A, Tang, W.-J.
登録日2010-08-15
公開日2010-09-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Ubiquitin is a novel substrate for human insulin-degrading enzyme.
J.Mol.Biol., 406, 2011
3MTN
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BU of 3mtn by Molmil
Usp21 in complex with a ubiquitin-based, USP21-specific inhibitor
分子名称: CHLORIDE ION, GLYCEROL, UBIQUITIN VARIANT UBV.21.4, ...
著者Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Ernst, A, Sidhu, S, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2010-04-30
公開日2010-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A strategy for modulation of enzymes in the ubiquitin system.
Science, 339, 2013
3PGE
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BU of 3pge by Molmil
Structure of sumoylated PCNA
分子名称: Proliferating cell nuclear antigen, SUMO-modified proliferating cell nuclear antigen
著者Freudenthal, B.D, Brogie, J.E, Gakhar, L, Washington, T.
登録日2010-11-01
公開日2010-12-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of SUMO-Modified Proliferating Cell Nuclear Antigen.
J.Mol.Biol., 406, 2011
3PHX
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BU of 3phx by Molmil
OTU Domain of Crimean Congo Hemorrhagic Fever Virus in complex with ISG15
分子名称: ACETIC ACID, ETHANAMINE, RNA-directed RNA polymerase L, ...
著者Akutsu, M, Ye, Y, Virdee, S, Komander, D.
登録日2010-11-04
公開日2011-02-02
最終更新日2014-08-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains.
Proc.Natl.Acad.Sci.USA, 108, 2011

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