5HPS
System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: WWP1 and UbV P1.1
Summary for 5HPS
Entry DOI | 10.2210/pdb5hps/pdb |
Related | 5HPK 5HPL 5HPT |
Descriptor | WWP1 HECT, Ubiquitin variant P1.1 (3 entities in total) |
Functional Keywords | hect, e3 ligase, ubiquitin variant, ubv, ligase |
Biological source | Homo sapiens More |
Total number of polymer chains | 2 |
Total formula weight | 54654.57 |
Authors | Wu, K.-P.,Mercredi, P.Y.,Schulman, B.A. (deposition date: 2016-01-20, release date: 2016-03-16, Last modification date: 2023-09-27) |
Primary citation | Zhang, W.,Wu, K.P.,Sartori, M.A.,Kamadurai, H.B.,Ordureau, A.,Jiang, C.,Mercredi, P.Y.,Murchie, R.,Hu, J.,Persaud, A.,Mukherjee, M.,Li, N.,Doye, A.,Walker, J.R.,Sheng, Y.,Hao, Z.,Li, Y.,Brown, K.R.,Lemichez, E.,Chen, J.,Tong, Y.,Harper, J.W.,Moffat, J.,Rotin, D.,Schulman, B.A.,Sidhu, S.S. System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol.Cell, 62:121-136, 2016 Cited by PubMed: 26949039DOI: 10.1016/j.molcel.2016.02.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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