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5HPS

System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: WWP1 and UbV P1.1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
WWP1 HECTpolymer38345134.61UniProt (Q9H0M0)
Pfam (PF00632)
Homo sapiensAtrophin-1-interacting protein 5,AIP5,TGIF-interacting ubiquitin ligase 1,Tiul1,WW domain-containing protein 1
2B
(B)
Ubiquitin variant P1.1polymer839520.01Pfam (PF00240)
UniProt (by SIFTS) (P62987)
Homo sapiens
3C, D
(A, B)
waterwater18.094Chemie (HOH)
Sequence modifications
A: 537 - 917 (UniProt: Q9H0M0)
PDBExternal DatabaseDetails
Gly 535-expression tag
Ser 536-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight54654.6
All*Total formula weight54654.6
*Water molecules are not included.

238268

PDB entries from 2025-07-02

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