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PDB: 338 件
3I3T
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BU of 3i3t by Molmil
Crystal structure of covalent ubiquitin-USP21 complex
分子名称: ETHANAMINE, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 21, ...
著者Neculai, D, Avvakumov, G.V, Walker, J.R, Xue, S, Butler-Cole, C, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2009-06-30
公開日2009-07-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献A strategy for modulation of enzymes in the ubiquitin system.
Science, 339, 2013
3LDZ
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BU of 3ldz by Molmil
Crystal structure of human STAM1 VHS domain in complex with ubiquitin
分子名称: Signal transducing adapter molecule 1, Ubiquitin
著者Ren, X, Hurley, J.H.
登録日2010-01-13
公開日2010-03-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献VHS domains of ESCRT-0 cooperate in high-avidity binding to polyubiquitinated cargo.
Embo J., 29, 2010
5N38
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BU of 5n38 by Molmil
S65DParkin and pUB complex
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase parkin,E3 ubiquitin-protein ligase parkin, ...
著者Kumar, A, Chaugule, V.K, Johnson, C, Toth, R, Sundaramoorthy, R, Knebel, A, Walden, H.
登録日2017-02-08
公開日2017-04-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.
Nat. Struct. Mol. Biol., 24, 2017
6A6I
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BU of 6a6i by Molmil
Crystal structure of the winged-helix domain of Cockayne syndrome group B protein in complex with ubiquitin
分子名称: CHLORIDE ION, Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant, ...
著者Takahashi, T.S, Sato, Y, Fukai, S.
登録日2018-06-28
公開日2019-02-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of ubiquitin recognition by the winged-helix domain of Cockayne syndrome group B protein.
Nucleic Acids Res., 47, 2019
3DVG
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BU of 3dvg by Molmil
Crystal structure of K63-specific fab Apu.3A8 bound to K63-linked di-ubiquitin
分子名称: Human IgG1 fab fragment heavy chain, Human IgG1 fab fragment light chain, Ubiquitin, ...
著者Hymowitz, S.G.
登録日2008-07-18
公開日2008-09-30
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies.
Cell(Cambridge,Mass.), 134, 2008
3N3K
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BU of 3n3k by Molmil
The catalytic domain of USP8 in complex with a USP8 specific inhibitor
分子名称: Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 8, ZINC ION
著者Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Allali-Hassani, A, Lam, R, Ernst, A, Sidhu, S, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium, Structural Genomics Consortium (SGC)
登録日2010-05-20
公開日2010-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A strategy for modulation of enzymes in the ubiquitin system.
Science, 339, 2013
2OJR
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BU of 2ojr by Molmil
Structure of ubiquitin solved by SAD using the Lanthanide-Binding Tag
分子名称: TERBIUM(III) ION, Ubiquitin
著者Silvaggi, N.R, Allen, K.N.
登録日2007-01-13
公開日2007-06-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Double-Lanthanide-Binding Tags for Macromolecular Crystallographic Structure Determination.
J.Am.Chem.Soc., 129, 2007
5TUT
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BU of 5tut by Molmil
UbcH5a-Ub isopeptide conjugate
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 D1
著者Sanchez, J.G, Wagner, J.M, Pornillos, O.
登録日2016-11-07
公開日2017-11-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.604 Å)
主引用文献UbcH5a-Ub isopeptide conjugate
To be Published
6BYH
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BU of 6byh by Molmil
Ubiquitin Variant (UbV.Fl11.1) bound to a human Skp1-Fbl11 fragment complex.
分子名称: Lysine-specific demethylase 2A, Polyubiquitin-B, S-phase kinase-associated protein 1
著者Manczyk, N, Sicheri, F.
登録日2017-12-20
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.
Structure, 26, 2018
5CAW
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BU of 5caw by Molmil
Structure of Pediculus humanus Parkin bound to phospho-ubiquitin
分子名称: E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, SULFATE ION, ...
著者Wauer, T, Komander, D.
登録日2015-06-30
公開日2015-07-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Mechanism of phospho-ubiquitin-induced PARKIN activation.
Nature, 524, 2015
5CRA
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BU of 5cra by Molmil
Structure of the SdeA DUB Domain
分子名称: METHYL 4-AMINOBUTANOATE, Polyubiquitin-B, SULFATE ION, ...
著者Sheedlo, M.J, Qiu, J, Luo, Z.Q, Das, C.
登録日2015-07-22
公開日2015-11-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Structural basis of substrate recognition by a bacterial deubiquitinase important for dynamics of phagosome ubiquitination.
Proc.Natl.Acad.Sci.USA, 112, 2015
7W54
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BU of 7w54 by Molmil
Crystal structure of a bacterial OTU DUB with Ub-PA
分子名称: Lpg2248, Polyubiquitin-B, prop-2-en-1-amine
著者Zhen, X, Ouyang, S.Y.
登録日2021-11-29
公開日2022-08-24
最終更新日2023-04-05
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Structural basis for the dual catalytic activity of the Legionella pneumophila ovarian tumor (OTU) domain deubiquitinase LotA.
J.Biol.Chem., 298, 2022
5D0K
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BU of 5d0k by Molmil
Structure of UbE2D2:RNF165:Ub complex
分子名称: Polyubiquitin-B, RING finger protein 165, Ubiquitin-conjugating enzyme E2 D2, ...
著者Wright, J.D, Day, C.L, Mace, P.D.
登録日2015-08-03
公開日2015-12-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity.
Nat.Struct.Mol.Biol., 23, 2016
6BVA
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BU of 6bva by Molmil
Ubiquitin Variant (UbV.Fl10.1) bound to a human Skp1-Fbl10 fragment complex.
分子名称: Lysine-specific demethylase 2B, Polyubiquitin-B, S-phase kinase-associated protein 1
著者Manczyk, N, Sicheri, F.
登録日2017-12-12
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.
Structure, 26, 2018
5N2W
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BU of 5n2w by Molmil
WT-Parkin and pUB complex
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase parkin,E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, ...
著者Kumar, A, Chaugule, V.K, Johnson, C, Toth, R, Sundaramoorthy, R, Knebel, A, Walden, H.
登録日2017-02-08
公開日2017-04-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.
Nat. Struct. Mol. Biol., 24, 2017
6JB6
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BU of 6jb6 by Molmil
Crystal structure of Ub-conjugated Ube2K C92K&K97A mutant (isopeptide linkage), 2.7 A resolution
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 K
著者Lee, J.-G, Youn, H.-S, Lee, Y, An, J.Y, Park, K.R, Kang, J.Y, Mun, S.A, Park, J, Park, T, Jin, M.W, Yang, J, Eom, S.H.
登録日2019-01-25
公開日2019-03-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of Ub-conjugated Ube2K C92K&K97A mutant (isopeptide linkage), 2.7 A resolution
To Be Published
6XAA
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BU of 6xaa by Molmil
SARS CoV-2 PLpro in complex with ubiquitin propargylamide
分子名称: Non-structural protein 3, Ubiquitin-propargylamide, ZINC ION
著者Klemm, T, Calleja, D.J, Richardson, L.W, Lechtenberg, B.C, Komander, D.
登録日2020-06-04
公開日2020-06-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2.
Embo J., 39, 2020
2Y5B
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BU of 2y5b by Molmil
Structure of USP21 in complex with linear diubiquitin-aldehyde
分子名称: SULFATE ION, UBIQUITIN, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 21, ...
著者Ye, Y, Akutsu, M, Reyes-Turcu, F, Enchev, R.I, Wilkinson, K.D, Komander, D.
登録日2011-01-12
公開日2012-01-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Polyubiquitin Binding and Cross-Reactivity in the Usp Domain Deubiquitinase Usp21.
Embo Rep., 12, 2011
1F9J
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BU of 1f9j by Molmil
STRUCTURE OF A NEW CRYSTAL FORM OF TETRAUBIQUITIN
分子名称: TETRAUBIQUITIN
著者Phillips, C.L, Thrower, J, Pickart, C.M, Hill, C.P.
登録日2000-07-10
公開日2001-02-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of a new crystal form of tetraubiquitin.
Acta Crystallogr.,Sect.D, 57, 2001
3PTF
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BU of 3ptf by Molmil
X-ray structure of the non-covalent complex between UbcH5A and Ubiquitin
分子名称: Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D1
著者Bosanac, I, Hymowitz, S.G.
登録日2010-12-02
公開日2011-05-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Modulation of K11-Linkage Formation by Variable Loop Residues within UbcH5A.
J.Mol.Biol., 408, 2011
3JSV
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BU of 3jsv by Molmil
Crystal structure of mouse NEMO CoZi in complex with Lys63-linked di-ubiquitin
分子名称: NF-kappa-B essential modulator, Ubiquitin
著者Yoshikawa, A, Sato, Y, Mimura, H, Yamashita, M, Yamagata, A, Fukai, S.
登録日2009-09-11
公開日2009-10-27
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the NEMO ubiquitin-binding domain in complex with Lys 63-linked di-ubiquitin
Febs Lett., 583, 2009
3DVN
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BU of 3dvn by Molmil
Crystal structure of K63-specific fab Apu2.16 bound to K63-linked di-ubiquitin
分子名称: Human IgG1 fab fragment heavy chain, Human IgG1 fab fragment light chain, Ubiquitin, ...
著者Hymowitz, S.G.
登録日2008-07-18
公開日2008-09-30
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies.
Cell(Cambridge,Mass.), 134, 2008
3MTN
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BU of 3mtn by Molmil
Usp21 in complex with a ubiquitin-based, USP21-specific inhibitor
分子名称: CHLORIDE ION, GLYCEROL, UBIQUITIN VARIANT UBV.21.4, ...
著者Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Ernst, A, Sidhu, S, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2010-04-30
公開日2010-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A strategy for modulation of enzymes in the ubiquitin system.
Science, 339, 2013
3O65
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BU of 3o65 by Molmil
Crystal structure of a Josephin-ubiquitin complex: Evolutionary restraints on ataxin-3 deubiquitinating activity
分子名称: Putative ataxin-3-like protein, SODIUM ION, Ubiquitin
著者Weeks, S.D, Grasty, K.C, Hernandez-Cuebas, L, Loll, P.J.
登録日2010-07-28
公開日2010-11-24
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of a Josephin-Ubiquitin Complex: EVOLUTIONARY RESTRAINTS ON ATAXIN-3 DEUBIQUITINATING ACTIVITY.
J.Biol.Chem., 286, 2011
2HTH
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BU of 2hth by Molmil
Structural basis for ubiquitin recognition by the human EAP45/ESCRT-II GLUE domain
分子名称: Ubiquitin, Vacuolar protein sorting protein 36
著者Alam, S.L, Whitby, F.G, Hill, C.P, Sundquist, W.I.
登録日2006-07-25
公開日2006-10-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain.
Nat.Struct.Mol.Biol., 13, 2006

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