5CAW

Structure of Pediculus humanus Parkin bound to phospho-ubiquitin

Summary for 5CAW

DescriptorE3 ubiquitin-protein ligase parkin, Polyubiquitin-B, ZINC ION, ... (5 entities in total)
Functional Keywordsubiquitin, parkin, pink1, phospho-ubiquitin, parkinson's disease, e3 ligase, rbr domain, mitophagy, cell signalling, signaling protein
Biological sourcePediculus humanus subsp. corporis (Body louse)
More
Cellular locationUbiquitin: Cytoplasm  P0CG47
Total number of polymer chains4
Total molecular weight91009.46
Authors
Wauer, T.,Komander, D. (deposition date: 2015-06-30, release date: 2015-07-22, Last modification date: 2017-09-13)
Primary citation
Wauer, T.,Simicek, M.,Schubert, A.,Komander, D.
Mechanism of phospho-ubiquitin-induced PARKIN activation.
Nature, 524:370-374, 2015
PubMed: 26161729 (PDB entries with the same primary citation)
DOI: 10.1038/nature14879
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.62 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.26040.1%0.6%2.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report