5CAW

Structure of Pediculus humanus Parkin bound to phospho-ubiquitin

Summary for 5CAW

Entry DOI	10.2210/pdb5caw/pdb
Descriptor	E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, ZINC ION, ... (5 entities in total)
Functional Keywords	ubiquitin, parkin, pink1, phospho-ubiquitin, parkinson's disease, e3 ligase, rbr domain, mitophagy, cell signalling, signaling protein
Biological source	Pediculus humanus subsp. corporis (Body louse) More
Cellular location	Ubiquitin: Cytoplasm : P0CG47
Total number of polymer chains	4
Total formula weight	91009.46
Authors	Wauer, T.,Komander, D. (deposition date: 2015-06-30, release date: 2015-07-22, Last modification date: 2024-01-10)
Primary citation	Wauer, T.,Simicek, M.,Schubert, A.,Komander, D. Mechanism of phospho-ubiquitin-induced PARKIN activation. Nature, 524:370-374, 2015 Cited by PubMed: 26161729 DOI: 10.1038/nature14879 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.62 Å)

Structure validation