6BVA
Ubiquitin Variant (UbV.Fl10.1) bound to a human Skp1-Fbl10 fragment complex.
Summary for 6BVA
Entry DOI | 10.2210/pdb6bva/pdb |
Descriptor | S-phase kinase-associated protein 1, Lysine-specific demethylase 2B, Polyubiquitin-B, ... (4 entities in total) |
Functional Keywords | ubiquitination, protein binding |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 68922.56 |
Authors | Manczyk, N.,Sicheri, F. (deposition date: 2017-12-12, release date: 2018-07-18, Last modification date: 2023-10-04) |
Primary citation | Gorelik, M.,Manczyk, N.,Pavlenco, A.,Kurinov, I.,Sidhu, S.S.,Sicheri, F. A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases. Structure, 26:1226-, 2018 Cited by PubMed: 30033217DOI: 10.1016/j.str.2018.06.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.66 Å) |
Structure validation
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