6BVA
Ubiquitin Variant (UbV.Fl10.1) bound to a human Skp1-Fbl10 fragment complex.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (D, C) | S-phase kinase-associated protein 1 | polymer | 165 | 18808.1 | 2 | UniProt (P63208) Pfam (PF03931) Pfam (PF01466) | Homo sapiens (Human) | Cyclin-A/CDK2-associated protein p19,p19A,Organ of Corti protein 2,OCP-2,Organ of Corti protein II,OCP-II,RNA polymerase II elongation factor-like protein,SIII,Transcription elongation factor B polypeptide 1-like,p19skp1 |
| 2 | B, F (E, F) | Lysine-specific demethylase 2B | polymer | 47 | 5680.7 | 2 | UniProt (Q8NHM5) Pfam (PF12937) | Homo sapiens (Human) | CXXC-type zinc finger protein 2,F-box and leucine-rich repeat protein 10,F-box protein FBL10,F-box/LRR-repeat protein 10,JmjC domain-containing histone demethylation protein 1B,Jumonji domain-containing EMSY-interactor methyltransferase motif protein,Protein JEMMA,Protein-containing CXXC domain 2,[Histone-H3]-lysine-36 demethylase 1B |
| 3 | C, D (B, A) | Polyubiquitin-B | polymer | 86 | 9972.5 | 2 | UniProt (P0CG47) Pfam (PF00240) | Homo sapiens (Human) | |
| 4 | G, H, I, J, K... (D, E, B, A, C...) | water | water | 18.0 | 40 | Chemie (HOH) |
Sequence modifications
D, C: 1 - 163 (UniProt: P63208)
E, F: 1060 - 1104 (UniProt: Q8NHM5)
B, A: 0 - 76 (UniProt: P0CG47)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 1058 | - | expression tag |
| Ala 1059 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Phe 8 | Leu 84 | engineered mutation |
| Arg 9 | Thr 85 | engineered mutation |
| Asp 10 | Gly 86 | engineered mutation |
| Arg 11 | Lys 87 | engineered mutation |
| Leu 11 | - | insertion |
| Arg 11 | - | insertion |
| Asn 11 | - | insertion |
| Leu 11 | - | insertion |
| Leu 11 | - | insertion |
| Pro 11 | - | insertion |
| Gln 11 | - | insertion |
| Val 42 | Arg 118 | engineered mutation |
| Ser 46 | Ala 122 | engineered mutation |
| Arg 47 | Gly 123 | engineered mutation |
| Arg 49 | Gln 125 | engineered mutation |
| Arg 68 | His 144 | engineered mutation |
| Val 72 | Arg 148 | engineered mutation |
| Phe 73 | Leu 149 | engineered mutation |
| Gly 74 | Arg 150 | engineered mutation |
| Arg 75 | Gly 151 | engineered mutation |
| Arg 76 | Gly 152 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 68922.6 | |
| All* | Total formula weight | 68922.6 |
