6BVA

Ubiquitin Variant (UbV.Fl10.1) bound to a human Skp1-Fbl10 fragment complex.

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0000082	biological_process	G1/S transition of mitotic cell cycle
C	0000209	biological_process	protein polyubiquitination
C	0000785	cellular_component	chromatin
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005813	cellular_component	centrosome
C	0005829	cellular_component	cytosol
C	0006338	biological_process	chromatin remodeling
C	0006355	biological_process	regulation of DNA-templated transcription
C	0006511	biological_process	ubiquitin-dependent protein catabolic process
C	0006879	biological_process	intracellular iron ion homeostasis
C	0007346	biological_process	regulation of mitotic cell cycle
C	0008013	molecular_function	beta-catenin binding
C	0010564	biological_process	regulation of cell cycle process
C	0010824	biological_process	regulation of centrosome duplication
C	0014033	biological_process	neural crest cell differentiation
C	0016567	biological_process	protein ubiquitination
C	0019005	cellular_component	SCF ubiquitin ligase complex
C	0019904	molecular_function	protein domain specific binding
C	0030510	biological_process	regulation of BMP signaling pathway
C	0031146	biological_process	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
C	0031467	cellular_component	Cul7-RING ubiquitin ligase complex
C	0031507	biological_process	heterochromatin formation
C	0031519	cellular_component	PcG protein complex
C	0032006	biological_process	regulation of TOR signaling
C	0042752	biological_process	regulation of circadian rhythm
C	0042981	biological_process	regulation of apoptotic process
C	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
C	0045892	biological_process	negative regulation of DNA-templated transcription
C	0050727	biological_process	regulation of inflammatory response
C	0051124	biological_process	synaptic assembly at neuromuscular junction
C	0051298	biological_process	centrosome duplication
C	0051457	biological_process	maintenance of protein location in nucleus
C	0051726	biological_process	regulation of cell cycle
C	0060173	biological_process	limb development
C	0060271	biological_process	cilium assembly
C	0070936	biological_process	protein K48-linked ubiquitination
C	0097602	molecular_function	cullin family protein binding
C	0140677	molecular_function	molecular function activator activity
C	0160072	molecular_function	ubiquitin ligase complex scaffold activity
C	1901524	biological_process	regulation of mitophagy
C	1904415	biological_process	regulation of xenophagy
C	1990444	molecular_function	F-box domain binding
C	1990756	molecular_function	ubiquitin-like ligase-substrate adaptor activity
C	1990757	molecular_function	ubiquitin ligase activator activity
C	2000001	biological_process	regulation of DNA damage checkpoint
D	0000082	biological_process	G1/S transition of mitotic cell cycle
D	0000209	biological_process	protein polyubiquitination
D	0000785	cellular_component	chromatin
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005813	cellular_component	centrosome
D	0005829	cellular_component	cytosol
D	0006338	biological_process	chromatin remodeling
D	0006355	biological_process	regulation of DNA-templated transcription
D	0006511	biological_process	ubiquitin-dependent protein catabolic process
D	0006879	biological_process	intracellular iron ion homeostasis
D	0007346	biological_process	regulation of mitotic cell cycle
D	0008013	molecular_function	beta-catenin binding
D	0010564	biological_process	regulation of cell cycle process
D	0010824	biological_process	regulation of centrosome duplication
D	0014033	biological_process	neural crest cell differentiation
D	0016567	biological_process	protein ubiquitination
D	0019005	cellular_component	SCF ubiquitin ligase complex
D	0019904	molecular_function	protein domain specific binding
D	0030510	biological_process	regulation of BMP signaling pathway
D	0031146	biological_process	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
D	0031467	cellular_component	Cul7-RING ubiquitin ligase complex
D	0031507	biological_process	heterochromatin formation
D	0031519	cellular_component	PcG protein complex
D	0032006	biological_process	regulation of TOR signaling
D	0042752	biological_process	regulation of circadian rhythm
D	0042981	biological_process	regulation of apoptotic process
D	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
D	0045892	biological_process	negative regulation of DNA-templated transcription
D	0050727	biological_process	regulation of inflammatory response
D	0051124	biological_process	synaptic assembly at neuromuscular junction
D	0051298	biological_process	centrosome duplication
D	0051457	biological_process	maintenance of protein location in nucleus
D	0051726	biological_process	regulation of cell cycle
D	0060173	biological_process	limb development
D	0060271	biological_process	cilium assembly
D	0070936	biological_process	protein K48-linked ubiquitination
D	0097602	molecular_function	cullin family protein binding
D	0140677	molecular_function	molecular function activator activity
D	0160072	molecular_function	ubiquitin ligase complex scaffold activity
D	1901524	biological_process	regulation of mitophagy
D	1904415	biological_process	regulation of xenophagy
D	1990444	molecular_function	F-box domain binding
D	1990756	molecular_function	ubiquitin-like ligase-substrate adaptor activity
D	1990757	molecular_function	ubiquitin ligase activator activity
D	2000001	biological_process	regulation of DNA damage checkpoint

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---