4BME
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![BU of 4bme by Molmil](/molmil-images/mine/4bme) | Crystal structure of the N terminal domain of human Galectin 8, F19Y mutant | Descriptor: | GALECTIN-8, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Buzamet, E, Ruiz, F.M, Menendez, M, Romero, A, Gabius, H.J, Solis, D. | Deposit date: | 2013-05-07 | Release date: | 2014-03-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Natural Single Amino Acid Polymorphism (F19Y) in Human Galectin-8: Detection of Structural Alterations and Increased Growth-Regulatory Activity on Tumor Cells. FEBS J., 281, 2014
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8BVH
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![BU of 8bvh by Molmil](/molmil-images/mine/8bvh) | |
8OKR
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![BU of 8okr by Molmil](/molmil-images/mine/8okr) | |
3TMP
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![BU of 3tmp by Molmil](/molmil-images/mine/3tmp) | The catalytic domain of human deubiquitinase DUBA in complex with ubiquitin aldehyde | Descriptor: | OTU domain-containing protein 5, Polyubiquitin-C | Authors: | Ma, X, Yin, J, Hymowitz, S, Starovasnik, M, Cochran, A. | Deposit date: | 2011-08-31 | Release date: | 2012-01-11 | Last modified: | 2012-02-29 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Phosphorylation-dependent activity of the deubiquitinase DUBA. Nat.Struct.Mol.Biol., 19, 2012
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4MNF
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![BU of 4mnf by Molmil](/molmil-images/mine/4mnf) | Crystal structure of BRAF-V600E bound to GDC0879 | Descriptor: | 2-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-inden-5-yl]-3-(pyridin-4-yl)-1H-pyrazol-1-yl}ethanol, CHLORIDE ION, Serine/threonine-protein kinase B-raf | Authors: | Sudhamsu, J, Haling, J.R, Morales, T, Brandhuber, B, Hymowitz, S.G. | Deposit date: | 2013-09-10 | Release date: | 2014-06-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.802 Å) | Cite: | Structure of the BRAF-MEK Complex Reveals a Kinase Activity Independent Role for BRAF in MAPK Signaling. Cancer Cell, 26, 2014
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3SQH
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3TMO
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![BU of 3tmo by Molmil](/molmil-images/mine/3tmo) | The catalytic domain of human deubiquitinase DUBA | Descriptor: | OTU domain-containing protein 5 | Authors: | Yin, J, Bosanac, I, Ma, X, Hymowitz, S, Starovasnik, M, Cochran, A. | Deposit date: | 2011-08-31 | Release date: | 2012-01-11 | Last modified: | 2012-02-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Phosphorylation-dependent activity of the deubiquitinase DUBA. Nat.Struct.Mol.Biol., 19, 2012
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4NRV
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![BU of 4nrv by Molmil](/molmil-images/mine/4nrv) | Crystal Structure of non-edited human NEIL1 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Endonuclease 8-like 1 | Authors: | Prakash, A, Doublie, S. | Deposit date: | 2013-11-27 | Release date: | 2014-01-01 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Genome and cancer single nucleotide polymorphisms of the human NEIL1 DNA glycosylase: Activity, structure, and the effect of editing. Dna Repair, 14, 2014
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4NRW
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![BU of 4nrw by Molmil](/molmil-images/mine/4nrw) | MvNei1-G86D | Descriptor: | 5'-D(*CP*GP*TP*CP*CP*AP*(3DR)P*GP*TP*CP*TP*AP*C)-3', 5'-D(*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3', formamidopyrimidine-DNA glycosylase | Authors: | Prakash, A, Doublie, S. | Deposit date: | 2013-11-27 | Release date: | 2014-01-01 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.845 Å) | Cite: | Genome and cancer single nucleotide polymorphisms of the human NEIL1 DNA glycosylase: Activity, structure, and the effect of editing. Dna Repair, 14, 2014
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3UW4
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![BU of 3uw4 by Molmil](/molmil-images/mine/3uw4) | Crystal structure of cIAP1 BIR3 bound to GDC0152 | Descriptor: | Baculoviral IAP repeat-containing protein 2, Baculoviral IAP repeat-containing protein 4, GDC0152, ... | Authors: | Maurer, B, Hymowitz, S. | Deposit date: | 2011-11-30 | Release date: | 2012-02-22 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152). J.Med.Chem., 55, 2012
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3NHD
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![BU of 3nhd by Molmil](/molmil-images/mine/3nhd) | GYVLGS segment 127-132 from human prion with V129 | Descriptor: | ACETIC ACID, Major prion protein | Authors: | Apostol, M.I, Eisenberg, D. | Deposit date: | 2010-06-14 | Release date: | 2010-08-04 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Crystallographic studies of prion protein (PrP) segments suggest how structural changes encoded by polymorphism at residue 129 modulate susceptibility to human prion disease. J.Biol.Chem., 285, 2010
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3NOK
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![BU of 3nok by Molmil](/molmil-images/mine/3nok) | Crystal structure of Myxococcus xanthus Glutaminyl Cyclase | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, ... | Authors: | Parthier, C, Carrillo, D.R, Stubbs, M.T. | Deposit date: | 2010-06-25 | Release date: | 2010-11-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Kinetic and structural characterization of bacterial glutaminyl cyclases from Zymomonas mobilis and Myxococcus xanthus Biol.Chem., 391, 2010
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4QM0
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![BU of 4qm0 by Molmil](/molmil-images/mine/4qm0) | Crystal structure of RORc in complex with a tertiary sulfonamide inverse agonist | Descriptor: | DIMETHYL SULFOXIDE, N-(2-methylpropyl)-N-({5-[4-(methylsulfonyl)phenyl]thiophen-2-yl}methyl)-1-phenylmethanesulfonamide, Nuclear receptor ROR-gamma | Authors: | Boenig, G, Hymowitz, S.G, Wang, W. | Deposit date: | 2014-06-14 | Release date: | 2014-09-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.195 Å) | Cite: | Reduction in lipophilicity improved the solubility, plasma-protein binding, and permeability of tertiary sulfonamide RORc inverse agonists. Bioorg.Med.Chem.Lett., 24, 2014
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3P08
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![BU of 3p08 by Molmil](/molmil-images/mine/3p08) | |
5LTM
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3NHC
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![BU of 3nhc by Molmil](/molmil-images/mine/3nhc) | GYMLGS segment 127-132 from human prion with M129 | Descriptor: | Major prion protein | Authors: | Apostol, M.I, Eisenberg, D. | Deposit date: | 2010-06-14 | Release date: | 2010-08-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Crystallographic studies of prion protein (PrP) segments suggest how structural changes encoded by polymorphism at residue 129 modulate susceptibility to human prion disease. J.Biol.Chem., 285, 2010
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3OJ4
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3OJ3
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2BI6
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![BU of 2bi6 by Molmil](/molmil-images/mine/2bi6) | NMR STUDY OF BROMELAIN INHIBITOR VI FROM PINEAPPLE STEM | Descriptor: | BROMELAIN INHIBITOR VI | Authors: | Hatano, K.-I. | Deposit date: | 1995-12-07 | Release date: | 1996-04-03 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Solution structure of bromelain inhibitor IV from pineapple stem: structural similarity with Bowman-Birk trypsin/chymotrypsin inhibitor from soybean. Biochemistry, 35, 1996
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4U1A
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![BU of 4u1a by Molmil](/molmil-images/mine/4u1a) | Crystal structure of human peroxisomal delta3,delta2, enoyl-CoA isomerase helix-10 deletion mutant (ISOB-ECI2) | Descriptor: | CHLORIDE ION, Enoyl-CoA delta isomerase 2 | Authors: | Onwukwe, G.U, Koski, M.K, Wierenga, R.K. | Deposit date: | 2014-07-15 | Release date: | 2014-12-24 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Human Delta (3) , Delta (2) -enoyl-CoA isomerase, type 2: a structural enzymology study on the catalytic role of its ACBP domain and helix-10. Febs J., 282, 2015
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3PUM
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![BU of 3pum by Molmil](/molmil-images/mine/3pum) | Crystal structure of P domain dimer of Norovirus VA207 | Descriptor: | Capsid | Authors: | Chen, Y, Tan, M, Xia, M, Hao, N, Zhang, X.C, Huang, P, Jiang, X, Li, X, Rao, Z. | Deposit date: | 2010-12-06 | Release date: | 2011-08-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.252 Å) | Cite: | Crystallography of a Lewis-binding norovirus, elucidation of strain-specificity to the polymorphic human histo-blood group antigens Plos Pathog., 7, 2011
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4U19
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![BU of 4u19 by Molmil](/molmil-images/mine/4u19) | Crystal structure of human peroxisomal delta3,delta2, enoyl-CoA isomerase V349A mutant (ISOA-ECI2) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Enoyl-CoA delta isomerase 2 | Authors: | Onwukwe, G.U, Koski, M.K, Wierenga, R.K. | Deposit date: | 2014-07-15 | Release date: | 2014-12-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Human Delta (3) , Delta (2) -enoyl-CoA isomerase, type 2: a structural enzymology study on the catalytic role of its ACBP domain and helix-10. Febs J., 282, 2015
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3PVD
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![BU of 3pvd by Molmil](/molmil-images/mine/3pvd) | Crystal structure of P domain dimer of Norovirus VA207 complexed with 3'-sialyl-Lewis x tetrasaccharide | Descriptor: | Capsid, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose | Authors: | Chen, Y, Tan, M, Xia, M, Hao, N, Zhang, X.C, Huang, P, Jiang, X, Li, X, Rao, Z. | Deposit date: | 2010-12-06 | Release date: | 2011-08-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystallography of a Lewis-binding norovirus, elucidation of strain-specificity to the polymorphic human histo-blood group antigens Plos Pathog., 7, 2011
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4U18
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![BU of 4u18 by Molmil](/molmil-images/mine/4u18) | Crystal structure of human peroxisomal delta3,delta2, enoyl-CoA isomerase (ISO-ECI2) | Descriptor: | CHLORIDE ION, Enoyl-CoA delta isomerase 2, mitochondrial, ... | Authors: | Onwukwe, G.U, Koski, M.K, Wierenga, R.K. | Deposit date: | 2014-07-15 | Release date: | 2014-12-24 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Human Delta (3) , Delta (2) -enoyl-CoA isomerase, type 2: a structural enzymology study on the catalytic role of its ACBP domain and helix-10. Febs J., 282, 2015
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3NOB
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![BU of 3nob by Molmil](/molmil-images/mine/3nob) | |