3NHC
GYMLGS segment 127-132 from human prion with M129
Summary for 3NHC
| Entry DOI | 10.2210/pdb3nhc/pdb |
| Related | 3NHD |
| Descriptor | Major prion protein (2 entities in total) |
| Functional Keywords | amyloid-like protofibril, protein fibril |
| Biological source | Homo sapiens (human) |
| Cellular location | Cell membrane; Lipid-anchor, GPI-anchor. Isoform 2: Cytoplasm: P04156 |
| Total number of polymer chains | 2 |
| Total formula weight | 1253.45 |
| Authors | Apostol, M.I.,Eisenberg, D. (deposition date: 2010-06-14, release date: 2010-08-04, Last modification date: 2024-02-21) |
| Primary citation | Apostol, M.I.,Sawaya, M.R.,Cascio, D.,Eisenberg, D. Crystallographic studies of prion protein (PrP) segments suggest how structural changes encoded by polymorphism at residue 129 modulate susceptibility to human prion disease. J.Biol.Chem., 285:29671-29675, 2010 Cited by PubMed: 20685658DOI: 10.1074/jbc.C110.158303 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.57 Å) |
Structure validation
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