3SQH

Crystal structure of prethrombin-2 mutant S195A in the the open form

Summary for 3SQH

Entry DOI	10.2210/pdb3sqh/pdb
Related	1HAG 3SQE
Descriptor	Thrombin light chain, heavy chain (2 entities in total)
Functional Keywords	serine protease, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Secreted, extracellular space: P00734
Total number of polymer chains	1
Total formula weight	33393.27
Authors	Pozzi, N.,Chen, Z.,Di Cera, E. (deposition date: 2011-07-05, release date: 2011-11-30, Last modification date: 2023-09-13)
Primary citation	Pozzi, N.,Chen, Z.,Zapata, F.,Pelc, L.A.,Barranco-Medina, S.,Di Cera, E. Crystal structures of prethrombin-2 reveal alternative conformations under identical solution conditions and the mechanism of zymogen activation. Biochemistry, 50:10195-10202, 2011 Cited by PubMed: 22049947 DOI: 10.1021/bi2015019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation