3SQE
Crystal structure of prethrombin-2 mutant S195A in the alternative form
Summary for 3SQE
| Entry DOI | 10.2210/pdb3sqe/pdb |
| Related | 1HAG 3SQH |
| Descriptor | Thrombin light chain, heavy chain, GLYCEROL (3 entities in total) |
| Functional Keywords | serine protease, prethrombin-2, hydrolase |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted, extracellular space: P00734 |
| Total number of polymer chains | 1 |
| Total formula weight | 33577.46 |
| Authors | Pozzi, N.,Chen, Z.,Di Cera, E. (deposition date: 2011-07-05, release date: 2011-11-30, Last modification date: 2023-09-13) |
| Primary citation | Pozzi, N.,Chen, Z.,Zapata, F.,Pelc, L.A.,Barranco-Medina, S.,Di Cera, E. Crystal structures of prethrombin-2 reveal alternative conformations under identical solution conditions and the mechanism of zymogen activation. Biochemistry, 50:10195-10202, 2011 Cited by PubMed: 22049947DOI: 10.1021/bi2015019 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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