3TMP

The catalytic domain of human deubiquitinase DUBA in complex with ubiquitin aldehyde

Summary for 3TMP

Related3TMO
DescriptorOTU domain-containing protein 5, Polyubiquitin-C (3 entities in total)
Functional Keywordsotu fold, deubiquitinase, phosphorylation, hydrolase-protein binding complex, hydrolase/protein binding
Biological sourceHomo sapiens (human)
Cellular locationUbiquitin: Cytoplasm (By similarity) P0CG48
Total number of polymer chains8
Total molecular weight119269.44
Authors
Ma, X.,Yin, J.,Hymowitz, S.,Starovasnik, M.,Cochran, A. (deposition date: 2011-08-31, release date: 2012-01-11, Last modification date: 2012-02-29)
Primary citation
Huang, O.W.,Ma, X.,Yin, J.,Flinders, J.,Maurer, T.,Kayagaki, N.,Phung, Q.,Bosanac, I.,Arnott, D.,Dixit, V.M.,Hymowitz, S.G.,Starovasnik, M.A.,Cochran, A.G.
Phosphorylation-dependent activity of the deubiquitinase DUBA.
Nat.Struct.Mol.Biol., 19:171-175, 2012
PubMed: 22245969 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb.2206
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.91 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.227700.5%5.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report