4U19
Crystal structure of human peroxisomal delta3,delta2, enoyl-CoA isomerase V349A mutant (ISOA-ECI2)
Summary for 4U19
| Entry DOI | 10.2210/pdb4u19/pdb |
| Descriptor | Enoyl-CoA delta isomerase 2, CHLORIDE ION, 1,2-ETHANEDIOL, ... (4 entities in total) |
| Functional Keywords | peci, enoy-coa isomerase, crotonase, beta-oxidation, isomerase |
| Biological source | Homo sapiens (Human) |
| Cellular location | Isoform 1: Mitochondrion . Isoform 2: Peroxisome matrix: O75521 |
| Total number of polymer chains | 3 |
| Total formula weight | 91778.96 |
| Authors | Onwukwe, G.U.,Koski, M.K.,Wierenga, R.K. (deposition date: 2014-07-15, release date: 2014-12-24, Last modification date: 2023-12-20) |
| Primary citation | Onwukwe, G.U.,Kursula, P.,Koski, M.K.,Schmitz, W.,Wierenga, R.K. Human Delta (3) , Delta (2) -enoyl-CoA isomerase, type 2: a structural enzymology study on the catalytic role of its ACBP domain and helix-10. Febs J., 282:746-768, 2015 Cited by PubMed: 25515061DOI: 10.1111/febs.13179 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.88 Å) |
Structure validation
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