Crystal structure of the A20 ZnF4, ubiquitin and UbcH5A complex

Summary for 3OJ4

DescriptorUbiquitin-conjugating enzyme E2 D1, Ubiquitin, Tumor necrosis factor alpha-induced protein 3, ... (4 entities in total)
Functional Keywordsubiquitin, zinc finger, ubiquitin conjugating enzyme, zinc ion, ligase-protein binding complex, ligase/protein binding
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm  P51668
Ubiquitin: Cytoplasm  P0CG47
Cytoplasm. A20p50: Cytoplasm P21580
Total number of polymer chains6
Total molecular weight63240.72
Bosanac, I.,Hymowitz, S.G. (deposition date: 2010-08-20, release date: 2010-12-08, Last modification date: 2018-01-24)
Primary citation
Bosanac, I.,Wertz, I.E.,Pan, B.,Yu, C.,Kusam, S.,Lam, C.,Phu, L.,Phung, Q.,Maurer, B.,Arnott, D.,Kirkpatrick, D.S.,Dixit, V.M.,Hymowitz, S.G.
Ubiquitin Binding to A20 ZnF4 Is Required for Modulation of NF-κB Signaling
Mol.Cell, 40:548-557, 2010
PubMed: 21095585 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2010.10.009
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.310804.7%4.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report