4NRV
Crystal Structure of non-edited human NEIL1
Summary for 4NRV
| Entry DOI | 10.2210/pdb4nrv/pdb |
| Related | 4NRW |
| Descriptor | Endonuclease 8-like 1, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL (3 entities in total) |
| Functional Keywords | zincless finger domain, dna glycosylase, helix two-turns helix motif, hydrolase, lyase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome: Q96FI4 |
| Total number of polymer chains | 1 |
| Total formula weight | 33776.60 |
| Authors | Prakash, A.,Doublie, S. (deposition date: 2013-11-27, release date: 2014-01-01, Last modification date: 2023-09-20) |
| Primary citation | Prakash, A.,Carroll, B.L.,Sweasy, J.B.,Wallace, S.S.,Doublie, S. Genome and cancer single nucleotide polymorphisms of the human NEIL1 DNA glycosylase: Activity, structure, and the effect of editing. Dna Repair, 14:17-26, 2014 Cited by PubMed: 24382305DOI: 10.1016/j.dnarep.2013.12.003 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.601 Å) |
Structure validation
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