4NRV

Crystal Structure of non-edited human NEIL1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Endonuclease 8-like 1	polymer	297	33654.5	1	UniProt (Q96FI4) Pfam (PF01149) Pfam (PF09292) In PDB	Homo sapiens (human)	DNA glycosylase/AP lyase Neil1, DNA-(apurinic or apyrimidinic site) lyase Neil1, Endonuclease VIII-like 1, FPG1, Nei homolog 1, NEH1, Nei-like protein 1
2	A	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	1	Chemie (TRS)
3		water	water		18.0	96	Chemie (HOH)

Sequence modifications

A: 2 - 290 (UniProt: Q96FI4)

PDB	External Database	Details
Ser 147	Asn 147	engineered mutation
Leu 291	-	expression tag
Glu 292	-	expression tag
His 293	-	expression tag
His 294	-	expression tag
His 295	-	expression tag
His 296	-	expression tag
His 297	-	expression tag
His 298	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	33654.5
Non-Polymers*	Number of molecules	1
	Total formula weight	122.1
All*	Total formula weight	33776.6

*Water molecules are not included.