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4NRV

Crystal Structure of non-edited human NEIL1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Endonuclease 8-like 1polymer29733654.51UniProt (Q96FI4)
Pfam (PF01149)
Pfam (PF09292)
Homo sapiens (human)DNA glycosylase/AP lyase Neil1, DNA-(apurinic or apyrimidinic site) lyase Neil1, Endonuclease VIII-like 1, FPG1, Nei homolog 1, NEH1, Nei-like protein 1
2B
(A)
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer122.11Chemie (TRS)
3C
(A)
waterwater18.096Chemie (HOH)
Sequence modifications
A: 2 - 290 (UniProt: Q96FI4)
PDBExternal DatabaseDetails
Ser 147Asn 147engineered mutation
Leu 291-expression tag
Glu 292-expression tag
His 293-expression tag
His 294-expression tag
His 295-expression tag
His 296-expression tag
His 297-expression tag
His 298-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33654.5
Non-Polymers*Number of molecules1
Total formula weight122.1
All*Total formula weight33776.6
*Water molecules are not included.

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PDB entries from 2025-06-11

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