Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5CHV
DownloadVisualize
BU of 5chv by Molmil
Crystal structure of USP18-ISG15 complex
Descriptor: CHLORIDE ION, SULFATE ION, Ubiquitin-like protein ISG15, ...
Authors:Fritz, G, Basters, A.
Deposit date:2015-07-10
Release date:2016-09-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.005 Å)
Cite:Structural basis of the specificity of USP18 toward ISG15.
Nat. Struct. Mol. Biol., 24, 2017
4IUM
DownloadVisualize
BU of 4ium by Molmil
Equine arteritis virus papain-like protease 2 (PLP2) covalently bound to ubiquitin
Descriptor: GLYCEROL, Ubiquitin, ZINC ION, ...
Authors:Bailey-Elkin, B.A, James, T.W, Mark, B.L.
Deposit date:2013-01-21
Release date:2013-02-13
Last modified:2013-03-20
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Deubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cells.
Proc.Natl.Acad.Sci.USA, 110, 2013
6A42
DownloadVisualize
BU of 6a42 by Molmil
R1EN(5-223)-ubiquitin fusion
Descriptor: ACETIC ACID, RNA-directed DNA polymerase homolog (R1),Polyubiquitin-C
Authors:Maita, N.
Deposit date:2018-06-19
Release date:2018-10-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure Determination of Ubiquitin by Fusion to a Protein That Forms a Highly Porous Crystal Lattice
J. Am. Chem. Soc., 140, 2018
5C1Z
DownloadVisualize
BU of 5c1z by Molmil
Parkin (UblR0RBR)
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ...
Authors:kumar, A, Aguirre, J.D, Condos, T.E.C, Martinez-Torres, R.J, Chaugule, V.K, Toth, R, Sundaramoorthy, R, Mercier, P, Knebel, A, Spratt, D.E, Barber, K.R, Shaw, G.S, Walden, H.
Deposit date:2015-06-15
Release date:2015-07-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
5C7J
DownloadVisualize
BU of 5c7j by Molmil
CRYSTAL STRUCTURE OF NEDD4 WITH A UB VARIANT
Descriptor: E3 ubiquitin-protein ligase NEDD4, Polyubiquitin-C
Authors:Walker, J.R, Hu, J, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC)
Deposit date:2015-06-24
Release date:2016-03-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
5CAW
DownloadVisualize
BU of 5caw by Molmil
Structure of Pediculus humanus Parkin bound to phospho-ubiquitin
Descriptor: E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, SULFATE ION, ...
Authors:Wauer, T, Komander, D.
Deposit date:2015-06-30
Release date:2015-07-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Mechanism of phospho-ubiquitin-induced PARKIN activation.
Nature, 524, 2015
4JQW
DownloadVisualize
BU of 4jqw by Molmil
Crystal Structure of a Complex of NOD1 CARD and Ubiquitin
Descriptor: Nucleotide-binding oligomerization domain-containing protein 1, PHOSPHATE ION, Polyubiquitin-C
Authors:Ver Heul, A.M, Gakhar, L, Piper, R.C, Ramaswamy, S.
Deposit date:2013-03-20
Release date:2014-03-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of a complex of NOD1 CARD and ubiquitin
Plos One, 9, 2014
6AQR
DownloadVisualize
BU of 6aqr by Molmil
SAGA DUB module Ubp8(C146A)/Sgf11/Sus1/Sgf73 bound to monoubiquitin
Descriptor: Polyubiquitin-C, SAGA-associated factor 11, SAGA-associated factor 73, ...
Authors:Morrow, M.E, Morgan, M.T, Wolberger, C.
Deposit date:2017-08-21
Release date:2018-07-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Active site alanine mutations convert deubiquitinases into high-affinity ubiquitin-binding proteins.
EMBO Rep., 19, 2018
4JIO
DownloadVisualize
BU of 4jio by Molmil
Bro1 V domain and ubiquitin
Descriptor: BRO1, Ubiquitin
Authors:Pashkova, N, Gakhar, L, Piper, R.C.
Deposit date:2013-03-06
Release date:2013-06-19
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The yeast alix homolog bro1 functions as a ubiquitin receptor for protein sorting into multivesicular endosomes.
Dev.Cell, 25, 2013
4K1R
DownloadVisualize
BU of 4k1r by Molmil
Crystal structure of Schizosaccharomyces pombe sst2 catalytic domain and Ubiquitin
Descriptor: 1,2-ETHANEDIOL, AMSH-like protease sst2, CHLORIDE ION, ...
Authors:Shrestha, R.K, Das, C.
Deposit date:2013-04-05
Release date:2014-04-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.632 Å)
Cite:Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product.
Biochemistry, 53, 2014
5CVM
DownloadVisualize
BU of 5cvm by Molmil
USP46~ubiquitin BEA covalent complex
Descriptor: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, ZINC ION
Authors:Harris, S.F, Yin, J.
Deposit date:2015-07-27
Release date:2015-10-07
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46.
Structure, 23, 2015
5CRA
DownloadVisualize
BU of 5cra by Molmil
Structure of the SdeA DUB Domain
Descriptor: METHYL 4-AMINOBUTANOATE, Polyubiquitin-B, SULFATE ION, ...
Authors:Sheedlo, M.J, Qiu, J, Luo, Z.Q, Das, C.
Deposit date:2015-07-22
Release date:2015-11-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structural basis of substrate recognition by a bacterial deubiquitinase important for dynamics of phagosome ubiquitination.
Proc.Natl.Acad.Sci.USA, 112, 2015
6B7O
DownloadVisualize
BU of 6b7o by Molmil
Crystal structure of Legionella effector sdeD (lpg2509) H67A in complex with ADP-ribosylated Ubiquitin
Descriptor: Polyubiquitin-C, SdeD (lpg2509) H67A, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
Authors:Mao, Y, Akturk, A, Wasilko, J.
Deposit date:2017-10-04
Release date:2018-04-18
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector.
Nature, 557, 2018
5D6J
DownloadVisualize
BU of 5d6j by Molmil
Crystal structure of a mycobacterial protein
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Acyl-CoA synthase, MAGNESIUM ION, ...
Authors:Li, W.J, Bi, L.J.
Deposit date:2015-08-12
Release date:2016-03-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of FadD32, an enzyme essential for mycolic acid biosynthesis in mycobacteria.
Sci Rep, 5, 2015
5CVN
DownloadVisualize
BU of 5cvn by Molmil
WDR48 (2-580):USP46~ubiquitin ternary complex
Descriptor: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, WD repeat-containing protein 48, ...
Authors:Harris, S.F, Yin, J.
Deposit date:2015-07-27
Release date:2015-10-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.36 Å)
Cite:Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46.
Structure, 23, 2015
6BI8
DownloadVisualize
BU of 6bi8 by Molmil
X-ray structure of MERS coronavirus papain-like protease in complex with human ISG15
Descriptor: 1,2-ETHANEDIOL, CITRIC ACID, GLYCEROL, ...
Authors:Clasman, J.C, Mesecar, A.D.
Deposit date:2017-11-01
Release date:2018-11-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.291 Å)
Cite:Decoupling deISGylating and deubiquitinating activities of the MERS virus papain-like protease.
Antiviral Res., 174, 2020
6BVA
DownloadVisualize
BU of 6bva by Molmil
Ubiquitin Variant (UbV.Fl10.1) bound to a human Skp1-Fbl10 fragment complex.
Descriptor: Lysine-specific demethylase 2B, Polyubiquitin-B, S-phase kinase-associated protein 1
Authors:Manczyk, N, Sicheri, F.
Deposit date:2017-12-12
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.
Structure, 26, 2018
6BYH
DownloadVisualize
BU of 6byh by Molmil
Ubiquitin Variant (UbV.Fl11.1) bound to a human Skp1-Fbl11 fragment complex.
Descriptor: Lysine-specific demethylase 2A, Polyubiquitin-B, S-phase kinase-associated protein 1
Authors:Manczyk, N, Sicheri, F.
Deposit date:2017-12-20
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.
Structure, 26, 2018
6ASR
DownloadVisualize
BU of 6asr by Molmil
REV1 UBM2 domain complex with ubiquitin
Descriptor: DNA repair protein REV1, NICKEL (II) ION, Ubiquitin
Authors:Miller, D.J.
Deposit date:2017-08-25
Release date:2018-06-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.356 Å)
Cite:Structures of REV1 UBM2 Domain Complex with Ubiquitin and with a Small-Molecule that Inhibits the REV1 UBM2-Ubiquitin Interaction.
J. Mol. Biol., 430, 2018
6BVB
DownloadVisualize
BU of 6bvb by Molmil
Crystal structure of HIF-2alpha-pVHL-elongin B-elongin C
Descriptor: Elongin-B, Elongin-C, Hypoxia-Inducible Factor 2 alpha, ...
Authors:Tarade, D, Ohh, M, Lee, J.E.
Deposit date:2017-12-12
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:HIF-2 alpha-pVHL complex reveals broad genotype-phenotype correlations in HIF-2 alpha-driven disease.
Nat Commun, 9, 2018
5CVO
DownloadVisualize
BU of 5cvo by Molmil
WDR48:USP46~ubiquitin ternary complex
Descriptor: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, WD repeat-containing protein 48, ...
Authors:Harris, S.F, Yin, J.
Deposit date:2015-07-27
Release date:2015-10-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.885 Å)
Cite:Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46.
Structure, 23, 2015
5ZQ5
DownloadVisualize
BU of 5zq5 by Molmil
SidE-Ubi
Descriptor: SidE, Ubiquitin
Authors:Wang, Y, Gao, A, Gao, P.
Deposit date:2018-04-17
Release date:2018-05-23
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (2.487 Å)
Cite:Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
4KSK
DownloadVisualize
BU of 4ksk by Molmil
Gumby/Fam105B in complex with ubiquitin
Descriptor: Polyubiquitin-C, Protein FAM105B, SULFATE ION
Authors:Ceccarelli, D.F, Juang, Y.-C, Sicheri, F.
Deposit date:2013-05-17
Release date:2013-06-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis.
Nature, 498, 2013
4KSL
DownloadVisualize
BU of 4ksl by Molmil
Gumby/Fam105B in complex with linear di-ubiquitin
Descriptor: Polyubiquitin-C, Protein FAM105B
Authors:Juang, Y.-C, Ceccarelli, D.F, Sicheri, F.
Deposit date:2013-05-17
Release date:2013-06-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis.
Nature, 498, 2013
4K95
DownloadVisualize
BU of 4k95 by Molmil
Crystal Structure of Parkin
Descriptor: E3 ubiquitin-protein ligase parkin, ZINC ION
Authors:Seirafi, M, Menade, M, Sauve, V, Kozlov, G, Trempe, J.-F, Nagar, B, Gehring, K.
Deposit date:2013-04-19
Release date:2013-05-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (6.499 Å)
Cite:Structure of parkin reveals mechanisms for ubiquitin ligase activation.
Science, 340, 2013

224931

PDB entries from 2024-09-11

PDB statisticsPDBj update infoContact PDBjnumon