6BVB
Crystal structure of HIF-2alpha-pVHL-elongin B-elongin C
Summary for 6BVB
Entry DOI | 10.2210/pdb6bvb/pdb |
Descriptor | von Hippel-Lindau disease tumor suppressor, Elongin-B, Elongin-C, ... (5 entities in total) |
Functional Keywords | e3 ubiquitin ligase, gene regulation |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 44890.91 |
Authors | Tarade, D.,Ohh, M.,Lee, J.E. (deposition date: 2017-12-12, release date: 2018-08-01, Last modification date: 2023-10-04) |
Primary citation | Tarade, D.,Robinson, C.M.,Lee, J.E.,Ohh, M. HIF-2 alpha-pVHL complex reveals broad genotype-phenotype correlations in HIF-2 alpha-driven disease. Nat Commun, 9:3359-3359, 2018 Cited by PubMed: 30135421DOI: 10.1038/s41467-018-05554-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.002 Å) |
Structure validation
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