6BVB
Crystal structure of HIF-2alpha-pVHL-elongin B-elongin C
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (V) | von Hippel-Lindau disease tumor suppressor | polymer | 162 | 18702.3 | 1 | UniProt (P40337) Pfam (PF01847) Pfam (PF17211) | Homo sapiens (Human) | Protein G7,pVHL |
| 2 | B (B) | Elongin-B | polymer | 118 | 13147.8 | 1 | UniProt (Q15370) Pfam (PF00240) | Homo sapiens (Human) | EloB,Elongin 18 kDa subunit,RNA polymerase II transcription factor SIII subunit B,SIII p18,Transcription elongation factor B polypeptide 2 |
| 3 | C (C) | Elongin-C | polymer | 96 | 10843.4 | 1 | UniProt (Q15369) Pfam (PF03931) | Homo sapiens (Human) | EloC,Elongin 15 kDa subunit,RNA polymerase II transcription factor SIII subunit C,SIII p15,Transcription elongation factor B polypeptide 1 |
| 4 | D (H) | Hypoxia-Inducible Factor 2 alpha | polymer | 19 | 2197.4 | 1 | Pfam (PF11413) UniProt (by SIFTS) (Q99814) | Homo sapiens | |
| 5 | E, F, G, H (V, B, C, H) | water | water | 18.0 | 102 | Chemie (HOH) |
Sequence modifications
V: 54 - 213 (UniProt: P40337)
| PDB | External Database | Details |
|---|---|---|
| Gly 52 | - | expression tag |
| Ser 53 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 44890.9 | |
| All* | Total formula weight | 44890.9 |
