6BI8
X-ray structure of MERS coronavirus papain-like protease in complex with human ISG15
Summary for 6BI8
Entry DOI | 10.2210/pdb6bi8/pdb |
Descriptor | ORF1a, Ubiquitin-like protein ISG15, TRIETHYLENE GLYCOL, ... (9 entities in total) |
Functional Keywords | complex, signaling protein, deisgylase, hydrolase, hydrolase-substrate complex, hydrolase/substrate |
Biological source | Human betacoronavirus 2c EMC/2012 More |
Total number of polymer chains | 4 |
Total formula weight | 93570.69 |
Authors | Clasman, J.C.,Mesecar, A.D. (deposition date: 2017-11-01, release date: 2018-11-07, Last modification date: 2023-10-04) |
Primary citation | Clasman, J.R.,Everett, R.K.,Srinivasan, K.,Mesecar, A.D. Decoupling deISGylating and deubiquitinating activities of the MERS virus papain-like protease. Antiviral Res., 174:104661-104661, 2020 Cited by PubMed: 31765674DOI: 10.1016/j.antiviral.2019.104661 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.291 Å) |
Structure validation
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