Parkin (UblR0RBR)

Summary for 5C1Z

DescriptorE3 ubiquitin-protein ligase parkin, ZINC ION, SULFATE ION, ... (6 entities in total)
Functional Keywordsligase
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm, cytosol  O60260
Total number of polymer chains2
Total molecular weight92927.98
Primary citation
Kumar, A.,Aguirre, J.D.,Condos, T.E.,Martinez-Torres, R.J.,Chaugule, V.K.,Toth, R.,Sundaramoorthy, R.,Mercier, P.,Knebel, A.,Spratt, D.E.,Barber, K.R.,Shaw, G.S.,Walden, H.
Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34:2506-2521, 2015
PubMed: 26254304 (PDB entries with the same primary citation)
DOI: 10.15252/embj.201592337
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.21620.1%3.4%8.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report