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2LGV
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BU of 2lgv by Molmil
Rbx1
Descriptor: E3 ubiquitin-protein ligase RBX1, ZINC ION
Authors:Spratt, D.E, Shaw, G.S.
Deposit date:2011-08-02
Release date:2012-03-28
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Selective recruitment of an e2~ubiquitin complex by an e3 ubiquitin ligase.
J.Biol.Chem., 287, 2012
2M9Y
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BU of 2m9y by Molmil
Solution Structure of the Catalytic Domain of HHARI
Descriptor: E3 ubiquitin-protein ligase ARIH1, ZINC ION
Authors:Mercier, P, Spratt, D.E, Shaw, G.S.
Deposit date:2013-06-24
Release date:2013-11-13
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure of the HHARI catalytic domain shows glimpses of a HECT E3 ligase.
Plos One, 8, 2013
2LWR
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BU of 2lwr by Molmil
Solution Structure of RING2 Domain from Parkin
Descriptor: SD01679p, ZINC ION
Authors:Mercier, P, Spratt, D.E, Manczyk, N, Shaw, G.S.
Deposit date:2012-08-06
Release date:2013-06-12
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A molecular explanation for the recessive nature of parkin-linked Parkinson's disease.
Nat Commun, 4, 2013
2M48
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BU of 2m48 by Molmil
Solution Structure of IBR-RING2 Tandem Domain from Parkin
Descriptor: E3 UBIQUITIN-PROTEIN LIGASE PARKIN, ZINC ION
Authors:Noh, Y.J, Mercier, P, Spratt, D.E, Shaw, G.S.
Deposit date:2013-01-30
Release date:2013-05-15
Last modified:2024-03-13
Method:SOLUTION NMR
Cite:A molecular explanation for the recessive nature of parkin-linked Parkinson's disease.
Nat Commun, 4, 2013
8F36
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BU of 8f36 by Molmil
Ubx Homeodomain NMR solution structure
Descriptor: Homeotic protein ultrabithorax
Authors:Beasley, S.A, Loss, J.W, Mekkaoui, F, Advocate, M.R, Spratt, D.E.
Deposit date:2022-11-09
Release date:2023-04-19
Method:SOLUTION NMR
Cite:Ubx Homeodomain NMR solution structure
To Be Published
8F37
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BU of 8f37 by Molmil
AbdA Homeodomain NMR Solution Structure
Descriptor: Homeobox protein abdominal-A
Authors:Beasley, S.A, Simons, R.A, Advocate, M.R, Mekkaoui, F, Spratt, D.E.
Deposit date:2022-11-09
Release date:2023-04-19
Method:SOLUTION NMR
Cite:AbdA Homeodomain NMR solution structure
To Be Published
5W87
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BU of 5w87 by Molmil
Crystal structure of the C-terminal lobe of the human HERC6 HECT domain
Descriptor: PHOSPHATE ION, Probable E3 ubiquitin-protein ligase HERC6
Authors:WANG, Y, BELLESIS, A.G, ROYER, W.E, SPRATT, D.E.
Deposit date:2017-06-21
Release date:2018-07-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:Crystal structure of the C-terminal lobe of the human HERC6 HECT domain
To Be Published
2LL7
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BU of 2ll7 by Molmil
Solution NMR structure of CaM bound to the eNOS CaM binding domain peptide
Descriptor: Calmodulin, Nitric oxide synthase, endothelial
Authors:Piazza, M, Futrega, K, Spratt, D.E, Guillemette, J.G, Dieckmann, T.
Deposit date:2011-10-29
Release date:2012-05-16
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure and Dynamics of Calmodulin (CaM) Bound to Nitric Oxide Synthase Peptides: Effects of a Phosphomimetic CaM Mutation.
Biochemistry, 51, 2012
5C23
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BU of 5c23 by Molmil
Parkin (S65DUblR0RBR)
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ...
Authors:Kumar, A, Aguirre, J.D, Condos, T.E.C, Martinez-Torres, R.J, Chaugule, V.K, Toth, R, Sundaramoorthy, R, Mercier, P, Knebel, A, Spratt, D.E, Barber, K.R, Shaw, G.S, Walden, H.
Deposit date:2015-06-15
Release date:2015-07-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
5C1Z
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BU of 5c1z by Molmil
Parkin (UblR0RBR)
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ...
Authors:kumar, A, Aguirre, J.D, Condos, T.E.C, Martinez-Torres, R.J, Chaugule, V.K, Toth, R, Sundaramoorthy, R, Mercier, P, Knebel, A, Spratt, D.E, Barber, K.R, Shaw, G.S, Walden, H.
Deposit date:2015-06-15
Release date:2015-07-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
2LL6
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BU of 2ll6 by Molmil
Solution NMR structure of CaM bound to iNOS CaM binding domain peptide
Descriptor: Calmodulin, Nitric oxide synthase, inducible
Authors:Piazza, M, Futrega, K, Spratt, D.E, Dieckmann, T, Guillemette, J.G.
Deposit date:2011-10-29
Release date:2012-05-16
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure and Dynamics of Calmodulin (CaM) Bound to Nitric Oxide Synthase Peptides: Effects of a Phosphomimetic CaM Mutation.
Biochemistry, 51, 2012
6TGK
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BU of 6tgk by Molmil
Domain swapped E6AP C-lobe dimer
Descriptor: ACETATE ION, CALCIUM ION, Ubiquitin-protein ligase E3A
Authors:Ries, L.K, Feiler, C, Lowe, L.D, Liess, A.K.L, Lorenz, S.
Deposit date:2019-11-16
Release date:2020-02-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of the catalytic C-lobe of the HECT-type ubiquitin ligase E6AP.
Protein Sci., 29, 2020

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