1Q6P
 
 | | THE STRUCTURE OF PHOSPHOTYROSINE PHOSPHATASE 1B IN COMPLEX WITH COMPOUND 6 | | 分子名称: | 4'-((2S)-2-(1H-1,2,3-BENZOTRIAZOL-1-YL)-3-{4-[DIFLUORO(PHOSPHONO)METHYL]PHENYL}-2-PHENYLPROPYL)-1,1'-BIPHENYL-3-YLPHOSPHONIC ACID, CHLORIDE ION, Protein-tyrosine phosphatase, ... | | 著者 | Scapin, G, Patel, S.B, Becker, J.W, Wang, Q, Desponts, C, Waddleton, D, Skorey, K, Cromlish, W, Bayly, C, Therien, M, Gauthier, J.Y, Li, C.S, Lau, C.K, Ramachandran, C, Kennedy, B.P, Asante-Appiah, E. | | 登録日 | 2003-08-13 | | 公開日 | 2003-09-30 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The Structural Basis for the Selectivity of Benzotriazole Inhibitors of Ptp1B
Biochemistry, 42, 2003
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1QZE
 | | HHR23a protein structure based on residual dipolar coupling data | | 分子名称: | UV excision repair protein RAD23 homolog A | | 著者 | Walters, K.J, Lech, P.J, Goh, A.M, Wang, Q, Howley, P.M. | | 登録日 | 2003-09-16 | | 公開日 | 2003-10-21 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | DNA-repair protein hHR23a alters its protein structure upon binding proteasomal subunit S5a
Proc.Natl.Acad.Sci.USA, 100, 2003
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8W8F
 | | human co-transcriptional RNA capping enzyme RNGTT-CMTR1 | | 分子名称: | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, DNA (36-MER), DNA (45-MER), ... | | 著者 | Li, Y, Wang, Q, Xu, Y, Li, Z. | | 登録日 | 2023-09-02 | | 公開日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Strcutures of co-transcriptional RNA capping enzymes on paused transcription complex
To Be Published
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8W8E
 | | human co-transcriptional RNA capping enzyme RNGTT | | 分子名称: | DNA (36-MER), DNA (45-MER), DNA-directed RNA polymerase II subunit E, ... | | 著者 | Li, Y, Wang, Q, Xu, Y, Li, Z. | | 登録日 | 2023-09-02 | | 公開日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Strcutures of co-transcriptional RNA capping enzymes on paused transcription complex
To Be Published
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7U4M
 | | Crystal structure of human GPX4-U46C in complex with LOC1886 | | 分子名称: | 1,2-ETHANEDIOL, 4-methoxy-1H-indole-2-carbaldehyde, Phospholipid hydroperoxide glutathione peroxidase | | 著者 | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Polychronidou, V, Soni, R.K, Xia, X, Stockwell, B.R. | | 登録日 | 2022-02-28 | | 公開日 | 2022-12-07 | | 最終更新日 | 2022-12-28 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
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7U4K
 | | Crystal structure of human GPX4-U46C-R152H in complex with ML162 | | 分子名称: | 1,2-ETHANEDIOL, 2-chloro-N-(3-chloro-4-methoxyphenyl)-N-[(1R)-2-oxo-2-[(2-phenylethyl)amino]-1-(thiophen-2-yl)ethyl]acetamide, Phospholipid hydroperoxide glutathione peroxidase | | 著者 | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Xia, X, Soni, R.K, Stockwell, B.R. | | 登録日 | 2022-02-28 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
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7U4I
 | | Crystal structure of human GPX4-U46C-R152H in complex with CDS9 | | 分子名称: | 2-bromo-N-[(thiophen-2-yl)methyl]acetamide, Phospholipid hydroperoxide glutathione peroxidase, THIOCYANATE ION | | 著者 | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Polychronidou, V, Soni, R.K, Xia, X, Stockwell, B.R. | | 登録日 | 2022-02-28 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
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7U4L
 | | Crystal structure of human GPX4-U46C in complex with MAC-5576 | | 分子名称: | Phospholipid hydroperoxide glutathione peroxidase, thiophene-2-carbaldehyde | | 著者 | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Polychronidou, V, Soni, R.K, Xia, X, Stockwell, B.R. | | 登録日 | 2022-02-28 | | 公開日 | 2022-12-07 | | 最終更新日 | 2022-12-28 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
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7U4J
 | | Crystal structure of human GPX4-U46C-R152H in complex with TMT10 | | 分子名称: | Phospholipid hydroperoxide glutathione peroxidase, THIOCYANATE ION, ~{N}-(3-chloranyl-4-methoxy-phenyl)ethanamide | | 著者 | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Polychronidou, V, Soni, R.K, Xia, X, Stockwell, B.R. | | 登録日 | 2022-02-28 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
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7U4N
 | | Crystal structure of human GPX4-U46C in complex with RSL3 | | 分子名称: | Phospholipid hydroperoxide glutathione peroxidase, methyl (1S,3R)-2-(chloroacetyl)-1-[4-(methoxycarbonyl)phenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate | | 著者 | Forouhar, F, Liu, H, Lin, A.J, Wang, Q, Xia, X, Soni, R.K, Stockwell, B.R. | | 登録日 | 2022-02-28 | | 公開日 | 2022-12-07 | | 最終更新日 | 2022-12-28 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Small-molecule allosteric inhibitors of GPX4.
Cell Chem Biol, 29, 2022
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5BR3
 | | Crystal structure of hemagglutinin of A/Taiwan/2/2013 (H6N1) in complex with LSTa | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ HA1 CHAIN, HEMAGGLUTININ HA2 CHAIN, ... | | 著者 | Ni, F, Kondrashkina, E, Wang, Q. | | 登録日 | 2015-05-29 | | 公開日 | 2015-08-12 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structural and Functional Studies of Influenza Virus A/H6 Hemagglutinin.
Plos One, 7, 2015
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5BQZ
 | | Crystal structure of hemagglutinin of A/Chicken/Guangdong/S1311/2010 (H6N6) in complex with human-like receptor LSTc | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ HA1 CHAIN, ... | | 著者 | Ni, F, Kondrashkina, E, Wang, Q. | | 登録日 | 2015-05-29 | | 公開日 | 2015-10-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Structural and Functional Studies of Influenza Virus A/H6 Hemagglutinin.
Plos One, 10, 2015
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4RAZ
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6LNI
 | | Cryo-EM structure of amyloid fibril formed by full-length human prion protein | | 分子名称: | Major prion protein | | 著者 | Wang, L.Q, Zhao, K, Yuan, H.Y, Wang, Q, Guan, Z.Y, Tao, J, Li, X.N, Hao, M.M, Chen, J, Zhang, D.L, Zhu, H.L, Yin, P, Liu, C, Liang, Y. | | 登録日 | 2019-12-30 | | 公開日 | 2020-06-10 | | 最終更新日 | 2020-06-24 | | 実験手法 | ELECTRON MICROSCOPY (2.702 Å) | | 主引用文献 | Cryo-EM structure of an amyloid fibril formed by full-length human prion protein.
Nat.Struct.Mol.Biol., 27, 2020
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7RPK
 | | Cryo-EM structure of murine Dispatched in complex with Sonic hedgehog | | 分子名称: | (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Asarnow, D, Wang, Q, Ding, K, Cheng, Y, Beachy, P.A. | | 登録日 | 2021-08-03 | | 公開日 | 2021-10-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Dispatched uses Na + flux to power release of lipid-modified Hedgehog.
Nature, 599, 2021
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7RPI
 | | Cryo-EM structure of murine Dispatched 'T' conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Lauryl Maltose Neopentyl Glycol, ... | | 著者 | Asarnow, D, Wang, Q, Ding, K, Cheng, Y, Beachy, P.A. | | 登録日 | 2021-08-03 | | 公開日 | 2021-10-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Dispatched uses Na + flux to power release of lipid-modified Hedgehog.
Nature, 599, 2021
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7RPH
 | | Cryo-EM structure of murine Dispatched 'R' conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Lauryl Maltose Neopentyl Glycol, ... | | 著者 | Asarnow, D, Wang, Q, Ding, K, Cheng, Y, Beachy, P.A. | | 登録日 | 2021-08-03 | | 公開日 | 2021-10-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Dispatched uses Na + flux to power release of lipid-modified Hedgehog.
Nature, 599, 2021
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7RPJ
 | | Cryo-EM structure of murine Dispatched NNN mutant | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Protein dispatched homolog 1 | | 著者 | Asarnow, D, Wang, Q, Ding, K, Cheng, Y, Beachy, P.A. | | 登録日 | 2021-08-03 | | 公開日 | 2021-10-27 | | 最終更新日 | 2021-11-24 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Dispatched uses Na + flux to power release of lipid-modified Hedgehog.
Nature, 599, 2021
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4J0C
 | | tannin acyl hydrolase from Lactobacillus plantarum (native structure) | | 分子名称: | DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, Tannase | | 著者 | Wu, M, Wang, Q, Peng, X, Wen, H, Chen, Q, McKinstry, W.J. | | 登録日 | 2013-01-30 | | 公開日 | 2013-05-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystal structure of tannase from Lactobacillus plantarum.
J.Mol.Biol., 425, 2013
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4J0K
 | | Tannin acyl hydrolase in complex with ethyl gallate | | 分子名称: | DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ... | | 著者 | Ren, B, Wu, M, Wang, Q, Peng, X, Wen, H, Chen, Q, McKinstry, W.J. | | 登録日 | 2013-01-31 | | 公開日 | 2013-05-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Crystal structure of tannase from Lactobacillus plantarum.
J.Mol.Biol., 425, 2013
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4J0D
 | | tannin acyl hydrolase from Lactobacillus plantarum (Cadmium) | | 分子名称: | CADMIUM ION, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, ... | | 著者 | Ren, B, Wu, M, Wang, Q, Peng, X, Wen, H, Chen, Q, McKinstry, W.J. | | 登録日 | 2013-01-30 | | 公開日 | 2013-05-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of tannase from Lactobacillus plantarum.
J.Mol.Biol., 425, 2013
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4J0H
 | | Tannin acyl hydrolase in complex with gallic acid | | 分子名称: | 3,4,5-trihydroxybenzoic acid, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, ... | | 著者 | Ren, B, Wu, M, Wang, Q, Peng, X, Wen, H, Chen, Q, McKinstry, W.J. | | 登録日 | 2013-01-30 | | 公開日 | 2013-05-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of tannase from Lactobacillus plantarum.
J.Mol.Biol., 425, 2013
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4DUI
 | | DARPIN D1 binding to tubulin beta chain (not in complex) | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) D1 | | 著者 | Pecqueur, L, Duellberg, C, Dreier, B, Wang, Q, Jiang, C, Pluckthun, A, Surrey, T, Gigant, B, Knossow, M. | | 登録日 | 2012-02-22 | | 公開日 | 2013-02-27 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | | 主引用文献 | An Anti-Tubulin Darpin Caps the Microtubule Plus-End
To be Published
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4JUI
 | | crystal structure of tannase from from Lactobacillus plantarum | | 分子名称: | DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ... | | 著者 | Ren, B, Wu, M, Wang, Q, Peng, X, Wen, H, McKinstry, W.J, Chen, Q. | | 登録日 | 2013-03-24 | | 公開日 | 2013-05-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of tannase from Lactobacillus plantarum.
J.Mol.Biol., 425, 2013
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4E41
 | | Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4 | | 分子名称: | HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ... | | 著者 | Deng, L, Langley, R.J, Wang, Q, Topalian, S.L, Mariuzza, R.A. | | 登録日 | 2012-03-11 | | 公開日 | 2012-08-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
Proc.Natl.Acad.Sci.USA, 2012
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