7RPJ

Cryo-EM structure of murine Dispatched NNN mutant

Summary for 7RPJ

Entry DOI	10.2210/pdb7rpj/pdb
EMDB information	24614 24615 24616 24617
Descriptor	Protein dispatched homolog 1, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE (3 entities in total)
Functional Keywords	rnd transporter, hedgehog binding, sterol sensing domain, sodium binding, membrane protein
Biological source	Mus musculus (Mouse)
Total number of polymer chains	1
Total formula weight	159988.39
Authors	Asarnow, D.,Wang, Q.,Ding, K.,Cheng, Y.,Beachy, P.A. (deposition date: 2021-08-03, release date: 2021-10-27, Last modification date: 2021-11-24)
Primary citation	Wang, Q.,Asarnow, D.E.,Ding, K.,Mann, R.K.,Hatakeyama, J.,Zhang, Y.,Ma, Y.,Cheng, Y.,Beachy, P.A. Dispatched uses Na + flux to power release of lipid-modified Hedgehog. Nature, 599:320-324, 2021 Cited by PubMed: 34707294 DOI: 10.1038/s41586-021-03996-0 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation