3Q7J
Engineered Thermoplasma Acidophilum F3 factor mimics human aminopeptidase N (APN) as a target for anticancer drug development
Summary for 3Q7J
Entry DOI | 10.2210/pdb3q7j/pdb |
Descriptor | Tricorn protease-interacting factor F3, ZINC ION, L-phenylalanyl-N6-[(benzyloxy)carbonyl]-N1-hydroxy-L-lysinamide, ... (4 entities in total) |
Functional Keywords | trf3, inhibitor fbo, aminopeptidase, inhibitor binding, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Thermoplasma acidophilum |
Cellular location | Cytoplasm: O93655 |
Total number of polymer chains | 2 |
Total formula weight | 179530.81 |
Authors | |
Primary citation | Su, J.,Wang, Q.,Feng, J.,Zhang, C.,Zhu, D.,Wei, T.,Xu, W.,Gu, L. Engineered Thermoplasma acidophilum factor F3 mimics human aminopeptidase N (APN) as a target for anticancer drug development Bioorg.Med.Chem., 19:2991-2996, 2011 Cited by PubMed: 21493078DOI: 10.1016/j.bmc.2011.03.028 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.91 Å) |
Structure validation
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