3Q7J
Engineered Thermoplasma Acidophilum F3 factor mimics human aminopeptidase N (APN) as a target for anticancer drug development
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tricorn protease-interacting factor F3 | polymer | 780 | 89478.7 | 2 | UniProt (O93655) Pfam (PF17900) Pfam (PF01433) Pfam (PF11838) | Thermoplasma acidophilum | |
| 2 | C, E (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D (A) | L-phenylalanyl-N6-[(benzyloxy)carbonyl]-N1-hydroxy-L-lysinamide | non-polymer | 442.5 | 1 | Chemie (FBO) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 17 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 780 (UniProt: O93655)
| PDB | External Database | Details |
|---|---|---|
| Gln 101 | Glu 101 | engineered mutation |
| Thr 261 | Asn 261 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 178957.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 573.3 | |
| All* | Total formula weight | 179530.8 |
