7RPH

Cryo-EM structure of murine Dispatched 'R' conformation

Summary for 7RPH

Entry DOI	10.2210/pdb7rph/pdb
EMDB information	24614 24615 24616 24617
Descriptor	Protein dispatched homolog 1, SODIUM ION, CHOLESTEROL HEMISUCCINATE, ... (6 entities in total)
Functional Keywords	rnd transporter, hedgehog binding, sterol sensing domain, sodium binding, membrane protein
Biological source	Mus musculus (Mouse)
Total number of polymer chains	1
Total formula weight	167911.40
Authors	Asarnow, D.,Wang, Q.,Ding, K.,Cheng, Y.,Beachy, P.A. (deposition date: 2021-08-03, release date: 2021-10-27, Last modification date: 2023-12-13)
Primary citation	Wang, Q.,Asarnow, D.E.,Ding, K.,Mann, R.K.,Hatakeyama, J.,Zhang, Y.,Ma, Y.,Cheng, Y.,Beachy, P.A. Dispatched uses Na + flux to power release of lipid-modified Hedgehog. Nature, 599:320-324, 2021 Cited by PubMed: 34707294 DOI: 10.1038/s41586-021-03996-0 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.5 Å)

Structure validation