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PDB: 12521 results

8VJS
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Cryo-EM structure of Tulane virus 9-6-17 variant capsid protein VP1 9-14-18 without DTT treatment
Descriptor: Capsid protein
Authors:Sun, C, Jiang, W.
Deposit date:2024-01-07
Release date:2024-02-07
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:The 2.6 angstrom Structure of a Tulane Virus Variant with Minor Mutations Leading to Receptor Change.
Biomolecules, 14, 2024
8VJR
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BU of 8vjr by Molmil
Cryo-EM structure of Tulane virus 9-6-17 variant capsid protein VP1 9-14-18, DTT-treated
Descriptor: Capsid protein
Authors:Sun, C, Jiang, W.
Deposit date:2024-01-07
Release date:2024-02-07
Method:ELECTRON MICROSCOPY (2.63 Å)
Cite:The 2.6 angstrom Structure of a Tulane Virus Variant with Minor Mutations Leading to Receptor Change.
Biomolecules, 14, 2024
3J9Z
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BU of 3j9z by Molmil
Activation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor G
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Li, W, Liu, Z, Koripella, R.K, Langlois, R, Sanyal, S, Frank, J.
Deposit date:2015-03-27
Release date:2015-07-01
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G.
Sci Adv, 1, 2015
4QP3
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BU of 4qp3 by Molmil
Crystal Structure of ERK2 in complex with (S)-2-((9H-purin-6-yl)amino)-3-phenylpropan-1-ol
Descriptor: (2S)-3-phenyl-2-(9H-purin-6-ylamino)propan-1-ol, Mitogen-activated protein kinase 1
Authors:Yin, J, Wang, W.
Deposit date:2014-06-22
Release date:2015-09-23
Last modified:2015-12-16
Method:X-RAY DIFFRACTION (2.599 Å)
Cite:Fragment-based discovery of potent ERK2 pyrrolopyrazine inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
3JAV
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BU of 3jav by Molmil
Structure of full-length IP3R1 channel in the apo-state determined by single particle cryo-EM
Descriptor: Inositol 1,4,5-trisphosphate receptor type 1
Authors:Fan, G, Baker, M.L, Wang, Z, Baker, M.R, Sinyagovskiy, P.A, Chiu, W, Ludtke, S.J, Serysheva, I.I.
Deposit date:2015-06-30
Release date:2015-10-07
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Gating machinery of InsP3R channels revealed by electron cryomicroscopy.
Nature, 527, 2015
3JBT
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BU of 3jbt by Molmil
Atomic structure of the Apaf-1 apoptosome
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Apoptotic protease-activating factor 1, Cytochrome c, ...
Authors:Zhou, M, Li, Y, Hu, Q, Bai, X, Huang, W, Yan, C, Scheres, S.H.W, Shi, Y.
Deposit date:2015-10-15
Release date:2015-11-18
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Atomic structure of the apoptosome: mechanism of cytochrome c- and dATP-mediated activation of Apaf-1
Genes Dev., 29, 2015
4Q8F
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Human DNA polymerase eta extending primer immediately after a phenanthriplatin adducted G
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, 5'-D(*AP*GP*TP*GP*TP*GP*AP*C)-3', 5'-D(*CP*AP*TP*CP*GP*TP*CP*AP*CP*AP*CP*T)-3', ...
Authors:Gregory, M.T, Yang, W.
Deposit date:2014-04-26
Release date:2014-07-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.797 Å)
Cite:Structural and mechanistic studies of polymerase eta bypass of phenanthriplatin DNA damage.
Proc.Natl.Acad.Sci.USA, 111, 2014
3JS6
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BU of 3js6 by Molmil
Crystal structure of apo psk41 parM protein
Descriptor: Uncharacterized ParM protein
Authors:Schumacher, M.A, Xu, W, Firth, N.
Deposit date:2009-09-09
Release date:2010-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure and filament dynamics of the pSK41 actin-like ParM protein: implications for plasmid DNA segregation.
J.Biol.Chem., 285, 2010
3K9P
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The crystal structure of E2-25K and ubiquitin complex
Descriptor: Ubiquitin, Ubiquitin-conjugating enzyme E2 K
Authors:Kang, G.B, Ko, S, Song, S.M, Lee, W, Eom, S.H.
Deposit date:2009-10-16
Release date:2010-09-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity
J.Biol.Chem., 285, 2010
8WWO
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BU of 8wwo by Molmil
Crystal structure of the AFSV topoisomerase ATPase domain in complex with AMPPNP
Descriptor: DNA topoisomerase 2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Kuang, W, Deng, Z.
Deposit date:2023-10-26
Release date:2024-02-21
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-function analysis of the ATPase domain of African swine fever virus topoisomerase.
Mbio, 15, 2024
4QGL
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BU of 4qgl by Molmil
Acireductone dioxygenase from Bacillus anthracis with three cadmium ions
Descriptor: Acireductone dioxygenase, CADMIUM ION
Authors:Milaczewska, A.M, Chruszcz, M, Majorek, K.A, Porebski, P.J, Borowski, T, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2014-05-23
Release date:2014-06-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Acireductone dioxygenase from Bacillus anthracis with three cadmium ions
To be Published
3J7A
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BU of 3j7a by Molmil
Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit
Descriptor: 18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein eS10, ...
Authors:Wong, W, Bai, X.C, Brown, A, Fernandez, I.S, Hanssen, E, Condron, M, Tan, Y.H, Baum, J, Scheres, S.H.W.
Deposit date:2014-06-03
Release date:2014-07-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
Elife, 3, 2014
4QP4
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BU of 4qp4 by Molmil
Crystal Structure of ERK2 in complex with N-cyclohexyl-9H-purin-6-amine
Descriptor: Mitogen-activated protein kinase 1, N-cyclohexyl-9H-purin-6-amine
Authors:Yin, J, Wang, W.
Deposit date:2014-06-22
Release date:2015-09-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Fragment-based discovery of potent ERK2 pyrrolopyrazine inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
4QPA
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BU of 4qpa by Molmil
Crystal Structure of ERK2 in complex with 7-(1-benzyl-1H-pyrazol-4-yl)-2-(pyridin-4-yl)-5H-pyrrolo[2,3-b]pyrazine
Descriptor: 7-(1-benzyl-1H-pyrazol-4-yl)-2-(pyridin-4-yl)-5H-pyrrolo[2,3-b]pyrazine, Mitogen-activated protein kinase 1
Authors:Yin, J, Wang, W.
Deposit date:2014-06-22
Release date:2015-09-23
Last modified:2015-12-16
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Fragment-based discovery of potent ERK2 pyrrolopyrazine inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
3JVJ
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BU of 3jvj by Molmil
Crystal structure of the bromodomain 1 in mouse Brd4
Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, GLYCEROL
Authors:Vollmuth, F, Blankenfeldt, W, Geyer, M.
Deposit date:2009-09-17
Release date:2009-10-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution
J.Biol.Chem., 284, 2009
8VJC
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BU of 8vjc by Molmil
Cryo-EM structure of short form insulin receptor (IR-A) with three IGF2 bound, asymmetric conformation.
Descriptor: Insulin-like growth factor II, Isoform Short of Insulin receptor
Authors:An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E.
Deposit date:2024-01-06
Release date:2024-03-27
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Activation of the insulin receptor by insulin-like growth factor 2.
Nat Commun, 15, 2024
3JBQ
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BU of 3jbq by Molmil
Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6
Descriptor: GafA domain of cone phosphodiesterase 6C, GafB domain of phosphodiesterase 2A, IgG1-kappa 2E8 heavy chain, ...
Authors:Zhang, Z, He, F, Constantine, R, Baker, M.L, Baehr, W, Schmid, M.F, Wensel, T.G, Agosto, M.A.
Deposit date:2015-09-17
Release date:2015-09-30
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (11 Å)
Cite:Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6.
J.Biol.Chem., 290, 2015
3JXR
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X-Ray structure of r[CGCG(5-fluoro)CG]2
Descriptor: r[CGCG(5-fluoro)CG]2
Authors:Adamiak, D.A, Milecki, J, Adamiak, R.W, Rypniewski, W.
Deposit date:2009-09-21
Release date:2010-02-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:The hydration and unusual hydrogen bonding in the crystal structure of an RNA duplex containing alternating CG base pairs
New J.Chem., 34, 2010
3JZ1
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BU of 3jz1 by Molmil
Crystal structure of human thrombin mutant N143P in E:Na+ form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, NITRATE ION, ...
Authors:Niu, W, Chen, Z, Bush-Pelc, L.A, Bah, A, Gandhi, P.S, Di Cera, E.
Deposit date:2009-09-22
Release date:2009-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Mutant N143P reveals how Na+ activates thrombin
J.Biol.Chem., 284, 2009
4QC2
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Crystal structure of lipopolysaccharide transport protein LptB in complex with ATP and Magnesium ions
Descriptor: ABC transporter related protein, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Wang, Z, Xiang, Q, Zhu, X, Dong, H, He, C, Wang, H, Zhang, Y, Wang, W, Dong, C.
Deposit date:2014-05-09
Release date:2014-10-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structural and functional studies of conserved nucleotide-binding protein LptB in lipopolysaccharide transport.
Biochem.Biophys.Res.Commun., 452, 2014
8X19
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BU of 8x19 by Molmil
Structure of nucleosome-bound SRCAP-C in the ADP-BeFx-bound state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y.
Deposit date:2023-11-06
Release date:2024-03-06
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural insights into histone exchange by human SRCAP complex.
Cell Discov, 10, 2024
8VJB
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BU of 8vjb by Molmil
Cryo-EM structure of short form insulin receptor (IR-A) with four IGF2 bound, symmetric conformation.
Descriptor: Insulin-like growth factor II, Isoform Short of Insulin receptor
Authors:An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E.
Deposit date:2024-01-06
Release date:2024-03-27
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Activation of the insulin receptor by insulin-like growth factor 2.
Nat Commun, 15, 2024
8VSI
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BU of 8vsi by Molmil
Mechanistic Insights Revealed by YbtPQ in the Occluded State
Descriptor: ABC transporter ATP-binding protein, ADP ORTHOVANADATE, MAGNESIUM ION, ...
Authors:Hu, W, Parkinson, C, Zheng, H.
Deposit date:2024-01-24
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mechanistic Insights Revealed by YbtPQ in the Occluded State.
Biomolecules, 14, 2024
4QEI
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Two distinct conformational states of GlyRS captured in crystal lattice
Descriptor: ADENOSINE MONOPHOSPHATE, Glycine--tRNA ligase, tRNA-Gly-CCC-2-2
Authors:Xie, W, Qin, X, Deng, X, Zhang, Q, Li, Q.
Deposit date:2014-05-16
Release date:2015-05-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.875 Å)
Cite:Large Conformational Changes of Insertion 3 in Human Glycyl-tRNA Synthetase (hGlyRS) during Catalysis
J.Biol.Chem., 291, 2016
3JZ2
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BU of 3jz2 by Molmil
Crystal structure of human thrombin mutant N143P in E* form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Thrombin heavy chain, ...
Authors:Niu, W, Chen, Z, Bush-Pelc, L.A, Bah, A, Gandhi, P.S, Di Cera, E.
Deposit date:2009-09-22
Release date:2009-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mutant N143P reveals how Na+ activates thrombin
J.Biol.Chem., 284, 2009

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