8WWO

Crystal structure of the AFSV topoisomerase ATPase domain in complex with AMPPNP

Summary for 8WWO

• Entry DOI: 10.2210/pdb8wwo/pdb
• Descriptor: DNA topoisomerase 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: topoisomerase, viral protein
• Biological source: African swine fever virus
• Total number of polymer chains: 4
• Total formula weight: 186815.21

Authors

Kuang, W.,Deng, Z. (deposition date: 2023-10-26, release date: 2024-02-21, Last modification date: 2024-07-10)

• Primary citation: Kuang, W.,Zhao, Y.,Li, J.,Deng, Z.; Structure-function analysis of the ATPase domain of African swine fever virus topoisomerase.; Mbio, 15:e0308623-e0308623, 2024; PubMed: 38411066; DOI: 10.1128/mbio.03086-23

Experimental method

X-RAY DIFFRACTION (2.2 Å)