3J7A

Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit

Summary for 3J7A

Related3J79
EMDB information2660 2661
Descriptor18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein uS2, ... (36 entities in total)
Functional Keywordsemetine, ribosome-inhibitor complex, ribosome/inhibitor
Biological sourcePlasmodium falciparum
Total number of polymer chains33
Total molecular weight1263059.92
Authors
Wong, W.,Bai, X.C.,Brown, A.,Fernandez, I.S.,Hanssen, E.,Condron, M.,Tan, Y.H.,Baum, J.,Scheres, S.H.W. (deposition date: 2014-06-03, release date: 2014-07-16, Last modification date: 2018-07-18)
Primary citation
Wong, W.,Bai, X.C.,Brown, A.,Fernandez, I.S.,Hanssen, E.,Condron, M.,Tan, Y.H.,Baum, J.,Scheres, S.H.
Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
Elife, 3:e03080-e03080, 2014
PubMed: 24913268 (PDB entries with the same primary citation)
DOI: 10.7554/eLife.03080
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
?

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone44.2%14.2%0.39MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 3j7a
no rotation
Molmil generated image of 3j7a
rotated about x axis by 90°
Molmil generated image of 3j7a
rotated about y axis by 90°
PDBj@FacebookPDBj@TwitterwwPDBwwPDB Foundation

Copyright © 2013-2018 Protein Data Bank Japan