3J7A

Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit

Summary for 3J7A

Related3J79
EMDB informationEMD-2660 EMD-2661
Descriptor18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein uS2, ... (36 entities in total)
Functional Keywordsemetine, ribosome-inhibitor complex, ribosome/inhibitor
Biological sourcePlasmodium falciparum
Total number of polymer chains33
Total molecular weight1263059.92
Authors
Wong, W.,Bai, X.C.,Brown, A.,Fernandez, I.S.,Hanssen, E.,Condron, M.,Tan, Y.H.,Baum, J.,Scheres, S.H.W. (deposition date: 2014-06-03, release date: 2014-07-16, Last modification date: 2018-07-18)
Primary citation
Wong, W.,Bai, X.C.,Brown, A.,Fernandez, I.S.,Hanssen, E.,Condron, M.,Tan, Y.H.,Baum, J.,Scheres, S.H.
Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
Elife, 3:e03080-e03080, 2014
PubMed: 24913268 (PDB entries with the same primary citation)
DOI: 10.7554/eLife.03080
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
?

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone44.2%14.2%0.39MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 3j7a
no rotation
Molmil generated image of 3j7a
rotated about x axis by 90°
Molmil generated image of 3j7a
rotated about y axis by 90°
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