3J7A
Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 18S ribosomal RNA | polymer | 2092 | 671337.5 | 1 | Plasmodium falciparum | ||
| 2 | B (B) | 40S ribosomal protein eS1 | polymer | 262 | 30111.7 | 1 | UniProt (O97313) Pfam (PF01015) | Plasmodium falciparum | |
| 3 | C (C) | 40S ribosomal protein uS2 | polymer | 263 | 29891.2 | 1 | UniProt (Q8IJD4) Pfam (PF00318) | Plasmodium falciparum | |
| 4 | D (D) | 40S ribosomal protein uS3 | polymer | 221 | 24709.9 | 1 | UniProt (Q8IKH8) Pfam (PF07650) Pfam (PF00189) | Plasmodium falciparum | |
| 5 | E (E) | 40S ribosomal protein uS4 | polymer | 189 | 22172.1 | 1 | UniProt (Q8I3R0) Pfam (PF00163) Pfam (PF01479) | Plasmodium falciparum | |
| 6 | F (F) | 40S ribosomal protein eS4 | polymer | 261 | 29830.3 | 1 | UniProt (Q8IIU8) Pfam (PF08071) Pfam (PF00900) Pfam (PF00467) Pfam (PF16121) | Plasmodium falciparum | |
| 7 | G (G) | 40S ribosomal protein uS5 | polymer | 272 | 30008.8 | 1 | UniProt (Q8IL02) Pfam (PF00333) Pfam (PF03719) | Plasmodium falciparum | |
| 8 | H (H) | 40S ribosomal protein eS6 | polymer | 306 | 35473.8 | 1 | UniProt (Q8IDR9) Pfam (PF01092) | Plasmodium falciparum | |
| 9 | I (I) | 40S ribosomal protein uS7 | polymer | 195 | 21898.5 | 1 | UniProt (Q8IBN5) Pfam (PF00177) | Plasmodium falciparum | |
| 10 | J (J) | 40S ribosomal protein eS7 | polymer | 194 | 22524.7 | 1 | UniProt (Q8IET7) Pfam (PF01251) | Plasmodium falciparum | |
| 11 | K (K) | 40S ribosomal protein uS8 | polymer | 130 | 14900.7 | 1 | UniProt (O77395) Pfam (PF00410) | Plasmodium falciparum | |
| 12 | L (L) | 40S ribosomal protein eS8 | polymer | 218 | 25106.0 | 1 | UniProt (Q8IM10) Pfam (PF01201) | Plasmodium falciparum | |
| 13 | M (M) | 40S ribosomal protein uS9 | polymer | 144 | 16318.2 | 1 | UniProt (Q8IAX5) Pfam (PF00380) | Plasmodium falciparum | |
| 14 | N (N) | 40S ribosomal protein uS10 | polymer | 118 | 13534.9 | 1 | UniProt (Q8IK02) Pfam (PF00338) | Plasmodium falciparum | |
| 15 | O (O) | 40S ribosomal protein eS10 | polymer | 137 | 16510.2 | 1 | UniProt (Q8IBQ5) Pfam (PF03501) | Plasmodium falciparum | |
| 16 | P (P) | 40S ribosomal protein uS11 | polymer | 151 | 16105.6 | 1 | UniProt (Q8I3U6) | Plasmodium falciparum | |
| 17 | Q (Q) | 40S ribosomal protein uS12 | polymer | 145 | 16167.0 | 1 | UniProt (O97248) Pfam (PF00164) | Plasmodium falciparum | |
| 18 | R (R) | 40S ribosomal protein eS12 | polymer | 141 | 15414.4 | 1 | UniProt (O97249) Pfam (PF01248) | Plasmodium falciparum | |
| 19 | S (S) | 40S ribosomal protein uS13 | polymer | 156 | 17928.9 | 1 | UniProt (Q8IIA2) Pfam (PF00416) | Plasmodium falciparum | |
| 20 | T (T) | 40S ribosomal protein uS14 | polymer | 54 | 6430.7 | 1 | UniProt (C0H4K8) Pfam (PF00253) | Plasmodium falciparum | |
| 21 | U (U) | 40S ribosomal protein uS15 | polymer | 151 | 17286.5 | 1 | UniProt (Q8IDB0) Pfam (PF08069) Pfam (PF00312) | Plasmodium falciparum | |
| 22 | V (V) | 40S ribosomal protein uS17 | polymer | 161 | 18801.2 | 1 | UniProt (O77381) Pfam (PF16205) Pfam (PF00366) | Plasmodium falciparum | |
| 23 | W (W) | 40S ribosomal protein eS17 | polymer | 137 | 16097.0 | 1 | UniProt (Q8I502) Pfam (PF00833) | Plasmodium falciparum | |
| 24 | X (X) | 40S ribosomal protein uS19 | polymer | 145 | 16800.8 | 1 | UniProt (C0H5C2) Pfam (PF00203) | Plasmodium falciparum | |
| 25 | Y (Y) | 40S ribosomal protein eS19 | polymer | 170 | 19757.9 | 1 | UniProt (Q8IFP2) Pfam (PF01090) | Plasmodium falciparum | |
| 26 | Z (Z) | 40S ribosomal protein eS21 | polymer | 82 | 9157.5 | 1 | UniProt (Q8IHS5) Pfam (PF01249) | Plasmodium falciparum | |
| 27 | AA (1) | 40S ribosomal protein eS24 | polymer | 133 | 15431.5 | 1 | UniProt (Q8I3R6) Pfam (PF01282) | Plasmodium falciparum | |
| 28 | BA (2) | 40S ribosomal protein eS25 | polymer | 105 | 11691.9 | 1 | UniProt (Q8ILN8) Pfam (PF03297) | Plasmodium falciparum | |
| 29 | CA (3) | 40S ribosomal protein eS26 | polymer | 107 | 12539.7 | 1 | UniProt (O96258) Pfam (PF01283) | Plasmodium falciparum | |
| 30 | DA (4) | 40S ribosomal protein eS27 | polymer | 82 | 9154.9 | 1 | UniProt (Q8IEN2) Pfam (PF01667) | Plasmodium falciparum | |
| 31 | EA (5) | 40S ribosomal protein eS28 | polymer | 67 | 7508.8 | 1 | UniProt (Q8IKL9) Pfam (PF01200) | Plasmodium falciparum | |
| 32 | FA (6) | 40S ribosomal protein eS30 | polymer | 58 | 6508.7 | 1 | UniProt (O96269) Pfam (PF04758) | Plasmodium falciparum | |
| 33 | GA (7) | tRNA | polymer | 74 | 23774.1 | 1 | Plasmodium falciparum | ||
| 34 | AB, AC, BB, BC, CB... (A) | MAGNESIUM ION | non-polymer | 24.3 | 67 | Chemie (MG) | |||
| 35 | PC (A) | emetine | non-polymer | 480.6 | 1 | Chemie (34G) | |||
| 36 | XC (T) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 33 |
| Total formula weight | 1260885.4 | |
| Non-Polymers* | Number of molecules | 69 |
| Total formula weight | 2174.5 | |
| All* | Total formula weight | 1263059.9 |
