4QEI

Two distinct conformational states of GlyRS captured in crystal lattice

Summary for 4QEI

• Entry DOI: 10.2210/pdb4qei/pdb
• Descriptor: Glycine--tRNA ligase, tRNA-Gly-CCC-2-2, ADENOSINE MONOPHOSPHATE, ... (4 entities in total)
• Functional Keywords: aminoacyl-trna synthetase, glycylation, glycyl-trna synthetase, trna ligase, ligase-rna complex, ligase/rna
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm : P41250
• Total number of polymer chains: 2
• Total formula weight: 94430.99

Authors

Xie, W.,Qin, X.,Deng, X.,Zhang, Q.,Li, Q. (deposition date: 2014-05-16, release date: 2015-05-20, Last modification date: 2023-11-08)

• Primary citation: Deng, X.,Qin, X.,Chen, L.,Jia, Q.,Zhang, Y.,Zhang, Z.,Lei, D.,Ren, G.,Zhou, Z.,Wang, Z.,Li, Q.,Xie, W.; Large Conformational Changes of Insertion 3 in Human Glycyl-tRNA Synthetase (hGlyRS) during Catalysis; J.Biol.Chem., 291:5740-5752, 2016; PubMed: 26797133; DOI: 10.1074/jbc.M115.679126

Experimental method

X-RAY DIFFRACTION (2.875 Å)