4QEI
Two distinct conformational states of GlyRS captured in crystal lattice
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glycine--tRNA ligase | polymer | 630 | 71757.7 | 1 | UniProt (P41250) Pfam (PF00587) Pfam (PF03129) | Homo sapiens (human) | Diadenosine tetraphosphate synthetase, AP-4-A synthetase, Glycyl-tRNA synthetase, GlyRS |
| 2 | B (C) | tRNA-Gly-CCC-2-2 | polymer | 69 | 22326.0 | 1 | GenBank (634721920) | Homo sapiens | |
| 3 | C (A) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) PubChem (16397049) PubChem (16760266) PubChem (224) PubChem (40467049) PubChem (40469468) PubChem (34768) PubChem (44348067) PubChem (83862) PubChem (45358029) PubChem (46874558) PubChem (40459109) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (46875232) PubChem (446048) PubChem (515384) PubChem (638042) PubChem (177678969) PubChem (6083) PubChem (1549371) PubChem (5316444) PubChem (92144436) PubChem (5742864) PubChem (122197642) PubChem (12358354) PubChem (12163610) PubChem (12358355) PubChem (162290139) PubChem (162946266) PubChem (171699505) | |||
| 4 | D, E (A, C) | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence modifications
A: 64 - 685 (UniProt: P41250)
| PDB | External Database | Details |
|---|---|---|
| Gly 71 | Glu 125 | engineered mutation |
| Arg 157 | Cys 211 | engineered mutation |
| Leu 686 | - | expression tag |
| Glu 687 | - | expression tag |
| His 688 | - | expression tag |
| His 689 | - | expression tag |
| His 690 | - | expression tag |
| His 691 | - | expression tag |
| His 692 | - | expression tag |
| His 693 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 94083.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 347.2 | |
| All* | Total formula weight | 94431.0 |
