4QEI
Two distinct conformational states of GlyRS captured in crystal lattice
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Glycine--tRNA ligase | polymer | 630 | 71757.7 | 1 | UniProt (P41250) Pfam (PF00587) Pfam (PF03129) | Homo sapiens (human) | Diadenosine tetraphosphate synthetase, AP-4-A synthetase, Glycyl-tRNA synthetase, GlyRS |
2 | B (C) | tRNA-Gly-CCC-2-2 | polymer | 69 | 22326.0 | 1 | GenBank (634721920) | Homo sapiens | |
3 | C (A) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) | |||
4 | D, E (A, C) | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence modifications
A: 64 - 685 (UniProt: P41250)
PDB | External Database | Details |
---|---|---|
Gly 71 | Glu 125 | engineered mutation |
Arg 157 | Cys 211 | engineered mutation |
Leu 686 | - | expression tag |
Glu 687 | - | expression tag |
His 688 | - | expression tag |
His 689 | - | expression tag |
His 690 | - | expression tag |
His 691 | - | expression tag |
His 692 | - | expression tag |
His 693 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 94083.8 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 347.2 | |
All* | Total formula weight | 94431.0 |