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4QEI

Two distinct conformational states of GlyRS captured in crystal lattice

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Glycine--tRNA ligasepolymer63071757.71UniProt (P41250)
Pfam (PF00587)
Pfam (PF03129)
Homo sapiens (human)Diadenosine tetraphosphate synthetase, AP-4-A synthetase, Glycyl-tRNA synthetase, GlyRS
2B
(C)
tRNA-Gly-CCC-2-2polymer6922326.01GenBank (634721920)Homo sapiens
3C
(A)
ADENOSINE MONOPHOSPHATEnon-polymer347.21Chemie (AMP)
4D, E
(A, C)
waterwater18.033Chemie (HOH)
Sequence modifications
A: 64 - 685 (UniProt: P41250)
PDBExternal DatabaseDetails
Gly 71Glu 125engineered mutation
Arg 157Cys 211engineered mutation
Leu 686-expression tag
Glu 687-expression tag
His 688-expression tag
His 689-expression tag
His 690-expression tag
His 691-expression tag
His 692-expression tag
His 693-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight94083.8
Non-Polymers*Number of molecules1
Total formula weight347.2
All*Total formula weight94431.0
*Water molecules are not included.

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PDB entries from 2024-10-30

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