3JBT
Atomic structure of the Apaf-1 apoptosome
Summary for 3JBT
Entry DOI | 10.2210/pdb3jbt/pdb |
EMDB information | 6480 |
Descriptor | Apoptotic protease-activating factor 1, Cytochrome c, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | apoptosome, cryo-em structure, apoptosis, apaf-1 |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 14 |
Total formula weight | 1096452.78 |
Authors | |
Primary citation | Zhou, M.,Li, Y.,Hu, Q.,Bai, X.C.,Huang, W.,Yan, C.,Scheres, S.H.W.,Shi, Y. Atomic structure of the apoptosome: mechanism of cytochrome c- and dATP-mediated activation of Apaf-1 Genes Dev., 29:2349-2361, 2015 Cited by PubMed: 26543158DOI: 10.1101/gad.272278.115 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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