3JBT
Atomic structure of the Apaf-1 apoptosome
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G, I... (A, C, E, G, I...) | Apoptotic protease-activating factor 1 | polymer | 1260 | 143647.3 | 7 | UniProt (O14727) Pfam (PF00619) Pfam (PF00400) Pfam (PF00931) Pfam (PF21296) Pfam (PF17908) | Homo sapiens (human) | APAF-1 |
| 2 | B, D, F, H, J... (B, D, F, H, J...) | Cytochrome c | polymer | 105 | 11856.8 | 7 | UniProt (P00004) Pfam (PF00034) | Equus caballus (horse) | |
| 3 | AA, DA, GA, O, R... (I, K, M, A, C...) | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE | non-polymer | 491.2 | 7 | Chemie (DTP) PubChem (622) PubChem (15993) PubChem (448808) PubChem (44119995) PubChem (46936612) PubChem (89346292) PubChem (57233913) PubChem (91632917) PubChem (92341128) PubChem (92449119) PubChem (92449120) PubChem (129069956) PubChem (171699368) | |||
| 4 | BA, EA, HA, P, S... (I, K, M, A, C...) | MAGNESIUM ION | non-polymer | 24.3 | 7 | Chemie (MG) PubChem (888) | |||
| 5 | CA, FA, IA, Q, T... (J, L, N, B, D...) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 7 | Chemie (HEM) |
Sequence modifications
A, C, E, G, I, K, M: 1 - 1248 (UniProt: O14727)
| PDB | External Database | Details |
|---|---|---|
| Leu 1249 | - | expression tag |
| Glu 1250 | - | expression tag |
| His 1251 | - | expression tag |
| His 1252 | - | expression tag |
| His 1253 | - | expression tag |
| His 1254 | - | expression tag |
| His 1255 | - | expression tag |
| His 1256 | - | expression tag |
| His 1257 | - | expression tag |
| His 1258 | - | expression tag |
| His 1259 | - | expression tag |
| His 1260 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 14 |
| Total formula weight | 1088529.0 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 7923.8 | |
| All* | Total formula weight | 1096452.8 |
