4Q8F

Human DNA polymerase eta extending primer immediately after a phenanthriplatin adducted G

Summary for 4Q8F

• Entry DOI: 10.2210/pdb4q8f/pdb
• Related: 4Q8E
• Descriptor: DNA polymerase eta, 5'-D(*CP*AP*TP*CP*GP*TP*CP*AP*CP*AP*CP*T)-3', 5'-D(*AP*GP*TP*GP*TP*GP*AP*C)-3', ... (7 entities in total)
• Functional Keywords: polymerase, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q9Y253
• Total number of polymer chains: 3
• Total formula weight: 56121.15

Authors

Gregory, M.T.,Yang, W. (deposition date: 2014-04-26, release date: 2014-07-02, Last modification date: 2024-02-28)

• Primary citation: Gregory, M.T.,Park, G.Y.,Johnstone, T.C.,Lee, Y.S.,Yang, W.,Lippard, S.J.; Structural and mechanistic studies of polymerase eta bypass of phenanthriplatin DNA damage.; Proc.Natl.Acad.Sci.USA, 111:9133-9138, 2014; PubMed: 24927576; DOI: 10.1073/pnas.1405739111

Experimental method

X-RAY DIFFRACTION (2.797 Å)