8JUZ
 
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8JUY
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8I4O
 | | Design of a split green fluorescent protein for sensing and tracking an beta-amyloid | | 分子名称: | Beta-amyloid, Split Green flourescent protein | | 著者 | Taegeun, Y, Jinsu, L, Jungmin, Y, Jungmin, C, Wondo, H, Song, J.J, Haksung, K. | | 登録日 | 2023-01-20 | | 公開日 | 2023-11-29 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Engineering of a Fluorescent Protein for a Sensing of an Intrinsically Disordered Protein through Transition in the Chromophore State.
Jacs Au, 3, 2023
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8U5H
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2LW8
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5UMB
 | | Crystal structure of ATPase domain of Malaria GRP78 with ADP bound | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chaperone DnaK, MAGNESIUM ION, ... | | 著者 | Chen, Y, Antoshchenko, T, Pizarro, J.C, Song, J.H, Park, H. | | 登録日 | 2017-01-26 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Repurposing drugs to target the malaria parasite unfolding protein response.
Sci Rep, 8, 2018
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7K7I
 | | Density-fitted Model Structure of Antibody Variable Domains of TyTx4 in Complex with PltB pentamer of Typhoid Toxin | | 分子名称: | Fab Heavy Chain Variable Domain, Fab Light Chain Variable Domain, Putative pertussis-like toxin subunit | | 著者 | Nguyen, T, Feathers, J.R, Fromme, J.C, Song, J. | | 登録日 | 2020-09-22 | | 公開日 | 2021-09-01 | | 最終更新日 | 2021-09-22 | | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | | 主引用文献 | The structural basis of Salmonella A 2 B 5 toxin neutralization by antibodies targeting the glycan-receptor binding subunits.
Cell Rep, 36, 2021
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7JSJ
 | | Structure of the NaCT-PF2 complex | | 分子名称: | (2R)-2-[2-(4-tert-butylphenyl)ethyl]-2-hydroxybutanedioic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ... | | 著者 | Sauer, D.B, Wang, B, Song, J, Rice, W.J, Wang, D.N. | | 登録日 | 2020-08-14 | | 公開日 | 2021-02-24 | | 最終更新日 | 2021-03-10 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Structure and inhibition mechanism of the human citrate transporter NaCT.
Nature, 591, 2021
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7JSK
 | | Structure of the NaCT-Citrate complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, SODIUM ION, ... | | 著者 | Sauer, D.B, Wang, B, Song, J, Rice, W.J, Wang, D.N. | | 登録日 | 2020-08-14 | | 公開日 | 2021-02-24 | | 最終更新日 | 2021-03-10 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Structure and inhibition mechanism of the human citrate transporter NaCT.
Nature, 591, 2021
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7K7H
 | | Density-fitted Model Structure of Antibody Variable Domains of TyTx1 in Complex with PltB pentamer of Typhoid Toxin | | 分子名称: | Fab Heavy Chain Variable Domain, Fab Light Chain Variable Domain, Pertussis like toxin subunit B, ... | | 著者 | Nguyen, T, Feathers, J.R, Fromme, J.C, Song, J. | | 登録日 | 2020-09-22 | | 公開日 | 2021-09-01 | | 最終更新日 | 2021-09-22 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | The structural basis of Salmonella A 2 B 5 toxin neutralization by antibodies targeting the glycan-receptor binding subunits.
Cell Rep, 36, 2021
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5GT5
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5GZN
 | | Structure of neutralizing antibody bound to Zika envelope protein | | 分子名称: | Antibody Heavy chain, Antibody light chain, Genome polyprotein | | 著者 | Wang, Q, Yang, H, Liu, X, Dai, L, Ma, T, Qi, J, Wong, G, Peng, R, Liu, S, Li, J, Li, S, Song, J, Liu, J, He, J, Yuan, H, Xiong, Y, Liao, Y, Li, J, Yang, J, Tong, Z, Griffin, B, Bi, Y, Liang, M, Xu, X, Cheng, G, Wang, P, Qiu, X, Kobinger, G, Shi, Y, Yan, J, Gao, G.F. | | 登録日 | 2016-09-29 | | 公開日 | 2016-12-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
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7JLT
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5GZO
 | | Structure of neutralizing antibody bound to Zika envelope protein | | 分子名称: | Antibody heavy chain, Antibody light chain, Genome polyprotein | | 著者 | Wang, Q, Yang, H, Liu, X, Dai, L, Ma, T, Qi, J, Wong, G, Peng, R, Liu, S, Li, J, Li, S, Song, J, Liu, J, He, J, Yuan, H, Xiong, Y, Liao, Y, Li, J, Yang, J, Tong, Z, Griffin, B, Bi, Y, Liang, M, Xu, X, Cheng, G, Wang, P, Qiu, X, Kobinger, G, Shi, Y, Yan, J, Gao, G.F. | | 登録日 | 2016-09-29 | | 公開日 | 2017-01-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.755 Å) | | 主引用文献 | Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
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5CH6
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5F1B
 | | Structural basis of Ebola virus entry: viral glycoprotein bound to its endosomal receptor Niemann-Pick C1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GP1, GP2, ... | | 著者 | Wang, H, Shi, Y, Song, J, Qi, J, Lu, G, Yan, J, Gao, G.F. | | 登録日 | 2015-11-30 | | 公開日 | 2016-01-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Ebola Viral Glycoprotein Bound to Its Endosomal Receptor Niemann-Pick C1.
Cell, 164, 2016
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5F18
 | | Structural basis of Ebola virus entry: viral glycoprotein bound to its endosomal receptor Niemann-Pick C1 | | 分子名称: | Niemann-Pick C1 protein | | 著者 | Wang, H, Shi, Y, Song, J, Qi, J, Lu, G, Yan, J, Gao, G.F. | | 登録日 | 2015-11-30 | | 公開日 | 2016-01-20 | | 最終更新日 | 2016-01-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Ebola Viral Glycoprotein Bound to Its Endosomal Receptor Niemann-Pick C1.
Cell, 164, 2016
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2PX9
 | | The intrinsic affinity between E2 and the Cys domain of E1 in Ubiquitin-like modifications | | 分子名称: | SUMO-activating enzyme subunit 2, SUMO-conjugating enzyme UBC9 | | 著者 | Wang, J.H, Hu, W.D, Cai, S, Lee, B, Song, J, Chen, Y. | | 登録日 | 2007-05-14 | | 公開日 | 2007-07-24 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The intrinsic affinity between E2 and the Cys domain of E1 in ubiquitin-like modifications.
Mol.Cell, 27, 2007
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5H3C
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8JEL
 | | Crystal structure of TIGIT in complexed with Ociperlimab, crystal form I | | 分子名称: | T-cell immunoreceptor with Ig and ITIM domains, antibody heavy chain, antibody light chain | | 著者 | Sun, J, Zhang, X.X, Song, J. | | 登録日 | 2023-05-16 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab.
Structure, 32, 2024
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8JEN
 | | Crystal structure of TIGIT in complexed with Ociperlimab, crystal form II | | 分子名称: | T-cell immunoreceptor with Ig and ITIM domains, antibody heavy chain, antibody light chain | | 著者 | Sun, J, Zhang, X.X, Song, J. | | 登録日 | 2023-05-16 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab.
Structure, 32, 2024
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5Y7W
 | | Crystal structure of the Nco-A1 PAS-B domain with YL-2 | | 分子名称: | Nuclear receptor coactivator 1, YL-2 peptide | | 著者 | Lee, Y.J, Yoon, H.S, Lee, J.H, Bae, J.H, Song, J.Y, Lim, H.S. | | 登録日 | 2017-08-18 | | 公開日 | 2017-11-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Targeted Inhibition of the NCOA1/STAT6 Protein-Protein Interaction
J. Am. Chem. Soc., 139, 2017
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5C6D
 | | Crystal structure of USP7 in complex with UHRF1 | | 分子名称: | E3 ubiquitin-protein ligase UHRF1, Ubiquitin carboxyl-terminal hydrolase 7 | | 著者 | Zhang, Z.-M, Song, J. | | 登録日 | 2015-06-22 | | 公開日 | 2015-09-09 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.292 Å) | | 主引用文献 | An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1.
Cell Rep, 12, 2015
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8JEP
 | | Crystal structure of Ociperlimab | | 分子名称: | antibody heavy chain, antibody light chain | | 著者 | Sun, J, Zhang, X.X, Song, J. | | 登録日 | 2023-05-16 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab.
Structure, 32, 2024
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8JEQ
 | | Crystal structure of Tiragolumab | | 分子名称: | antibody heavy chain, antibody light chain | | 著者 | Sun, J, Zhang, X.X, Song, J. | | 登録日 | 2023-05-16 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab.
Structure, 32, 2024
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