5Y7W
Crystal structure of the Nco-A1 PAS-B domain with YL-2
Summary for 5Y7W
Entry DOI | 10.2210/pdb5y7w/pdb |
Descriptor | Nuclear receptor coactivator 1, YL-2 peptide (3 entities in total) |
Functional Keywords | inflammatory allergic diseases and cancers, nuclear receptor coactivator 1, stapled peptide, transcription-inihibitor complex, transcription/inihibitor |
Biological source | Mus musculus (Mouse) More |
Cellular location | Nucleus : P70365 |
Total number of polymer chains | 4 |
Total formula weight | 32673.50 |
Authors | Lee, Y.J.,Yoon, H.S.,Lee, J.H.,Bae, J.H.,Song, J.Y.,Lim, H.S. (deposition date: 2017-08-18, release date: 2017-11-15, Last modification date: 2023-11-22) |
Primary citation | Lee, Y.,Yoon, H.,Hwang, S.M.,Shin, M.K.,Lee, J.H.,Oh, M.,Im, S.H.,Song, J.,Lim, H.S. Targeted Inhibition of the NCOA1/STAT6 Protein-Protein Interaction J. Am. Chem. Soc., 139:16056-16059, 2017 Cited by PubMed: 29090910DOI: 10.1021/jacs.7b08972 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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