7K7I

Density-fitted Model Structure of Antibody Variable Domains of TyTx4 in Complex with PltB pentamer of Typhoid Toxin

Summary for 7K7I

Entry DOI	10.2210/pdb7k7i/pdb
EMDB information	22700
Descriptor	Putative pertussis-like toxin subunit, Fab Light Chain Variable Domain, Fab Heavy Chain Variable Domain (3 entities in total)
Functional Keywords	typhoid toxin, a2b5, antibody, fab, toxin
Biological source	Salmonella typhi More
Total number of polymer chains	15
Total formula weight	187382.82
Authors	Nguyen, T.,Feathers, J.R.,Fromme, J.C.,Song, J. (deposition date: 2020-09-22, release date: 2021-09-01, Last modification date: 2021-09-22)
Primary citation	Nguyen, T.,Richards, A.F.,Neupane, D.P.,Feathers, J.R.,Yang, Y.A.,Sim, J.H.,Byun, H.,Lee, S.,Ahn, C.,Van Slyke, G.,Fromme, J.C.,Mantis, N.J.,Song, J. The structural basis of Salmonella A 2 B 5 toxin neutralization by antibodies targeting the glycan-receptor binding subunits. Cell Rep, 36:109654-109654, 2021 Cited by PubMed: 34496256 DOI: 10.1016/j.celrep.2021.109654 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.13 Å)

Structure validation